Division of Immunology and Infectious Diseases

Projects

Projects per year 1995 2002 2003 2005 2006 2007 2008 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2021 2022 2029

• 31 Active
• 376 Finished

Projects per year

Search results

• Active

  Scalable purification of viral vectors by metal affinity chromatography

  Gowripalan, A. (PI) & Tscharke, D. (CoI)

  20/06/25 → 19/06/26

  Project: Research

  • Affinity Chromatography 100%
  • Chromatography 100%

• Hudson Genome Bioinformatics Platforms Service

  Wu, P. (PI) & Andrews, D. (CoI)

  12/03/25 → 12/03/28

  Project: Research

• Advancing a vaccinia virus based prophylactic vaccine for DFT1

  Gowripalan, A. (PI), Flies, A. S. (CoI), Ong, C. (CoI), Tscharke, D. (CoI), Whitworth, D. J. (CoI) & Whitworth, D. J. (CoI)

  23/01/25 → 23/01/27

  Project: Research

  • Diseases 100%
  • Vaccinia Virus 100%
  • Face Tumor 100%
  • Vaccinia Vaccine 50%

• Investigating the phenotype and functions of CD10- Neutrophlis in MS

  Bruestle, A. (PI)

  1/01/25 → 31/12/27

  Project: Research

• Precision Medicine for Indigenous Australians: Epigenetic biomarkers to improve cardiometabolic disease prediction, management and prevention

  Buckberry, S. (PI)

  1/01/25 → 31/12/29

  Project: Research

  • Biological Marker 100%
  • Personalized Medicine 100%
  • Diseases 100%
  • Maturity Onset Diabetes of the Young 33%
  • Life Expectancy 33%

• The Centre of Excellence for Nucleic Acid Sensing

  Ellyard, J. (PI) & Walkley, C. R. (PI)

  1/11/24 → 30/10/29

  Project: Research

  • Nucleic Acid 100%
  • interferon 50%
  • Pathogen-Associated Molecular Pattern 50%
  • Self Molecule 50%
  • Interferon Type I 40%

• Fatigue In Relapsing Multiple Sclerosis-Epstein Barr Virus (EBV) Treatment Trial (FIRMS-EBV)

  Bruestle, A. (PI), Hardy, T. (PI), Hardy, T. (PI), Barton, J. (CoI), Butzkueven, H. (CoI), Gaudieri, S. (CoI), Giovannoni, G. (CoI), Kilpatrick, T. J. (CoI), Lloyd, A. (CoI), Monif, M. (CoI), Parratt, J. (CoI), Phan, T. G. (CoI), Ponsonby, A.-L. (CoI), Potter, A. (CoI), Spelman, T. (CoI), Vucic, O. (CoI) & Vucic, O. (CoI)

  28/08/24 → 28/08/29

  Project: Research

• Applying OCCAMS molecular razor to study the role of EBV in MS pathogenesis

  Bruestle, A. (PI), Phan, T. (PI), Andrews, T. (CoI), Ballouz, S. (CoI), Deenick, E. (CoI), Desborough, J. (CoI), Goodnow, C. C. (CoI), Hewitt, A. (CoI), Jackson, K. J. L. (CoI), John, N. A. (CoI), Massey, J. (CoI), Palendira, U. (CoI), Parnell, G. P. (CoI), Parnell, G. P. (CoI), Tscharke, D. (CoI), Yazar, S. (CoI) & Zaunders, J. J. (CoI)

  16/08/24 → 31/05/27

  Project: Research

• Accredited Cytokine Testing and Deep Immunophenotyping Facility

  Randall, K. (PI), Bruestle, A. (CoI), Davies, A. (CoI), Desborough, J. (CoI) & Nolan, C. (CoI)

  30/06/24 → 2/03/28

  Project: Research

• Comprehensive Immunophenotyping to identify novel treatment targets in refractory autoimmune kidney disease

  Jiang, S. (PI)

  11/01/24 → 31/07/25

  Project: Research

• MS Australia Senior Fellowship: Utilising the innate immune system to improve monitoring and treatment development in Multiple Sclerosis

  Bruestle, A. (PI)

  1/01/24 → 31/12/28

  Project: Research

  • Innate Immune System 100%
  • Multiple Sclerosis 50%
  • B Cell 50%
  • Cell Population 50%
  • Adaptive Immune System 50%

• Gene Therapy for Neurofibromatosis types 1 and 2

  Burgio, G. (PI), Schindeler, A. (PI), Schindeler, A. (PI), Berman, Y. (CoI), Dabscheck, G. (CoI) & Ginn, S. (CoI)

  1/01/24 → 31/12/27

  Project: Research

  • Neurofibromatosis Type I 100%
  • Neurofibromatosis Type II 100%
  • Gene Therapy 100%
  • Adeno Associated Virus Vector 100%
  • Neurofibromatosis Type 2 100%

• Harnessing inflammasome pathways against bacterial infection

  Man, S. M. (PI)

  1/01/24 → 31/12/28

  Project: Research

  • Multidrug Resistance 100%
  • Immune System 50%
  • Inflammasome 50%
  • Bacterial Infection 50%
  • Diseases 50%

• Development of a novel therapeutic inhibitor in the treatment of glomerulonephritis

  Jiang, S. (PI)

  31/07/23 → 31/07/25

  Project: Research

• Improving genetic diagnosis of autoimmune and autoinflammatory disease through an integrated multi-omics approach

  Jiang, S. (PI), Alexander, S. (CoI), Alexander, S. (CoI), Andrews, D. (CoI), Ascher, D. (CoI), Ascher, D. (CoI), Athanasopoulos, V. (CoI), Chakera, A. (CoI), Day, J. (CoI), Morrisroe, K. (CoI), Nikpour, M. (CoI), Randall, K. (CoI), Wicks, I. (CoI) & Yu, D. (CoI)

  1/06/23 → 31/05/27

  Project: Research

  • Multi-Omics 100%
  • Autoimmune Disease 50%
  • Autoinflammatory Syndromes 50%
  • Genetic Risk 16%
  • Transcriptomics 16%

• The missing heritability of human disease: discovery to implementation

  Buckberry, S. (PI), Ravenscroft, G. (PI), Arts, P. (CoI), Clark, M. (CoI), Deveson, I. (CoI), Eyk, C. V. (CoI), Homan, C. (CoI), Jackson, M. (CoI), Kumar, K. (CoI), Sallevelt, S. (CoI) & Venugopal, P. (CoI)

  1/02/23 → 31/01/28

  Project: Research

  • Genetics 100%
  • Genomics 33%
  • Genetic Screening 33%

• Personalised medicine in the treatment of complex autoimmunity and autoinflammatory disease

  Jiang, S. (PI), Andrews, D. (CoI), Athanasopoulos, V. (CoI), Chakera, A. (CoI), Morrisroe, K. (CoI), Randall, K. (CoI), Rogers, N. (CoI), Rogers, N. (CoI) & Walters, G. (CoI)

  1/02/23 → 31/01/27

  Project: Research

  • Autoinflammatory Syndromes 100%
  • Autoimmunity 100%
  • Autoimmune Disease 50%
  • Artificial Intelligence 25%
  • Genetic Variability 25%

• Therapeutic targeting of TLR7 in autoimmunity

  Ellyard, J. (PI), Gantier, M. (PI) & Corry, B. (CoI)

  1/01/23 → 31/12/26

  Project: Research

  • TLR7 100%
  • Autoimmunity 50%

• mRNA Activation Program - Novel enzymes to transform the manufacturing of mRNA in Victoria

  Burgio, G. (PI)

  30/09/22 → 20/01/26

  Project: Research

  • Enzyme 100%
  • Messenger RNA 100%
  • Polymerase 66%
  • Genetics 33%

• A multiparameter platform for novel radio-immunotherapy personalisation in metastatic colorectal cancer

  Quah, B. (PI), Syed, F. (PI), Atmosukarto, I. (CoI), Elsaleh, H. (CoI), Hammill, D. (CoI), Jack, C. (CoI), Jung, K. Y. K. (CoI), Price, J. (CoI), Selvaraj, J. (CoI), Simon Davis, D. (CoI) & Yip, D. (CoI)

  18/08/22 → 17/08/25

  Project: Research

  • Clinical Trial Design 100%
  • Metastatic Colorectal Cancer 100%
  • Immunotherapy 50%

• Canberra Clinical Phenomics

  Randall, K. (PI), Bertram, E. (CoI), Jiang, S. (CoI), Liu, M. (CoI) & McNaughton, E. (CoI)

  1/07/22 → 1/09/25

  Project: Research

  • Phenomics 100%
  • Clinical Trial 100%
  • Genomics 50%
  • Personalized Medicine 16%
  • Clinician 16%

• Refining the ObjectiveFIELD Analyser with particular reference to diabetes and neuro-ophthalmic diseases

  Maddess, T. (PI), Carle, C. (CoI), Rai, B. (CoI), Rai, B. (CoI), Van Kleef, J. (CoI) & Van Kleef, J. (CoI)

  1/07/22 → 30/11/25

  Project: Research

  • Agents Acting on the Eye 100%
  • Diseases 50%
  • Macular Degeneration 50%
  • Glaucoma 50%
  • Multiple Sclerosis 50%

• RNA-binding proteins rewire transcriptomes in immune cell differentiation

  Wen, J. (PI), Cockburn, I. (CoI), Parker, B. (CoI) & Tscharke, D. (CoI)

  1/06/22 → 31/05/26

  Project: Research

  • RNA Binding Protein 100%
  • Transcriptome 100%
  • Cell Differentiation 100%
  • Immunocompetent Cell 100%
  • Protein RNA Binding 100%

• A20 variants contribute to endemic kidney disease in Tiwi Islanders

  Jiang, S. (PI) & McMorran, B. (CoI)

  1/01/22 → 31/12/25

  Project: Research

  • Genetics 100%

• Understanding natural and vaccine-induced immunity to malaria

  Cockburn, I. (PI)

  1/01/22 → 31/12/26

  Project: Research

  • Plasmodium 100%
  • Immune Response 100%
  • Vaccine Development 100%
  • Malaria Vaccine 50%
  • Immune System 50%

• Pursuing IRF4 as a therapeutic opportunity for lymphoid malignancies

  Enders, A. (PI) & Casarotto, M. (CoI)

  1/01/22 → 31/12/25

  Project: Research

  • Interferon Regulatory Factor 4 100%
  • Lymphoma 50%
  • Mouse Model 20%
  • Neoplasm 20%
  • Immune System 20%

• Reducing the burden of DNA viruses on human health

  Tscharke, D. (PI)

  1/01/22 → 31/12/26

  Project: Research

  • Virus DNA 100%
  • Cold Sore 62%
  • Multiple Sclerosis 62%
  • Leukocyte 62%
  • DNA Virus 50%

• Antimicrobial immune proteins in the host defence against infectious diseases

  Man, S. M. (PI)

  1/01/21 → 31/12/25

  Project: Research

• Irradiation Immunity Interaction Lab (ICube)

  Quah, B. (PI), Atmosukarto, I. (CoI), Elsaleh, H. (CoI), Hannan, R. (CoI), Nguyen, B. (CoI), Selvaraj, J. (CoI), Simon Davis, D. (CoI) & Syed, F. (CoI)

  1/04/20 → 30/06/28

  Project: Research

• Kidney Disease in the Tiwi people

  McMorran, B. (PI), Easteal, S. (CoI), Hermes, A. (CoI), Jiang, S. (CoI) & Patel, H. (CoI)

  1/01/20 → 31/12/26

  Project: Research

  • Health Care Personnel 100%
  • Kidney Disease 100%
  • Diseases 100%
  • Nephropathy 100%
  • Clinician 100%

• Establishment of the Canberra Clinical Genomic Service and Research Service Agreement July 2020 - June 2025

  Bertram, E. (PI) & Cook, M. (CoI)

  1/03/17 → 30/06/26

  Project: Research

• Finished

  Discovering new anti-cancer drugs for the treatment of blood cancer

  Talaulikar, D. (PI), Man, S. M. (CoI) & Pandey, A. (CoI)

  18/12/24 → 6/07/25

  Project: Research

• Characterising and measuring fatigue in progressive multiple sclerosis; a person centered approach

  Bruestle, A. (PI), Cherbuin, N. (CoI), Desborough, J. (CoI), Fanning, V. (CoI) & Suominen, H. (CoI)

  1/01/24 → 31/03/25

  Project: Research

  • Multiple Sclerosis 100%

• Analysis of Slc1a5 KO mice

  Enders, A. (PI)

  8/09/23 → 31/12/24

  Project: Research

• How does sensing of DNA and DNA damage contribute to the development of cancer?

  Man, S. M. (PI)

  1/09/23 → 30/04/24

  Project: Research

  • Malignant Neoplasm 100%
  • DNA Damage 100%
  • Prognostic Biomarker 100%
  • Awareness 100%
  • Gene Targeting 100%

• Evaluation of CSIROs technology for RNA innovation

  Eyras, E. (PI) & Burgio, G. (CoI)

  1/07/23 → 31/03/25

  Project: Research

  • Service Contract 100%

• Investigating the genetic and molecular basis of autoimmune kidney disease

  Jiang, S. (PI)

  1/01/23 → 31/12/23

  Project: Research

• In vivo study of TLR7 inhibition in mice.

  Ellyard, J. (PI)

  21/12/22 → 1/06/23

  Project: Research

• Material Transfer and Evaluation Agreement: Testing the immune response to SARS-CoV-2 Spike subunit vaccine

  Man, S. M. (PI)

  12/08/22 → 12/08/23

  Project: Research

  • SARS Coronavirus 100%
  • Subunit Vaccine 50%
  • Enzyme-Linked Immunosorbent Assay 50%
  • Clinical Trial 25%
  • Toxicology 25%

• NHMRC Small Equipment Grant 2022 - Developing 3D organoid drug screening platforms to improve pre-clinical outcomes - Link to ARIES 41237

  Quinn, L. (PI), Arkell, R. (CoI), Barratt, K. (CoI), George, A. (CoI) & Hein, N. (CoI)

  22/07/22 → 31/12/23

  Project: Research

• NHMRC Small Equipment Grant 2022 - Luna FX7 Automated Cell Counter - Link to ARIES 41237

  Shirokikh, N. (PI), Bruestle, A. (CoI), Burgio, G. (CoI), Enders, A. (CoI), Eyras, E. (CoI), Fischer, T. (CoI), Hayashi, R. (CoI), McMorran, B. (CoI), Preiss, T. (CoI) & Schulte, K.-M. (CoI)

  22/07/22 → 31/12/23

  Project: Research

• How does sensing of DNA and DNA damage contribute to the development of colorectal cancer

  Mathur, A. (PI), Man, S. M. (CoI) & Teoh, N. (CoI)

  1/06/22 → 31/05/23

  Project: Research

  • DNA Damage 100%
  • Colorectal Carcinoma 50%
  • Intestine Cancer 50%
  • Colorectal Cancer 50%

• The role of innate immune sensor in the development of colorectal cancer

  Enosi Tuipulotu, D. (PI), Man, S. M. (CoI) & Pandey, A. (CoI)

  26/05/22 → 26/06/23

  Project: Research

• NHMRC Equipment Grant 2021: Colony Counter and Spiral Plating System - Linked to ARIES ID 39296

  Man, S. M. (PI), Burgio, G. (CoI), Li, R. (CoI), McMorran, B. (CoI), Natoli, R. (CoI), Talaulikar, D. (CoI) & Thompson, B. (CoI)

  6/10/21 → 31/12/21

  Project: Research

  • Colony Forming Unit S 100%
  • Bacterium Culture 100%
  • Microbiology 100%
  • Agar 100%
  • Bacterium Colony 100%

• NHMRC Equipment Grant 2021: ACDT Equipment - Linked to ARIES ID 39296

  Hannan, R. (PI), Burgio, G. (CoI), Dehorter, N. (CoI), Fischer, T. (CoI), Gardiner, E. (CoI), George, A. (CoI), McMorran, B. (CoI), Palmer, S. (CoI), Schulte, K.-M. (CoI), Shirokikh, N. (CoI) & Soboleva, T. (CoI)

  6/10/21 → 31/12/21

  Project: Research

  • Equipment 100%

• Research activities in relation to various Client compounds to be tested in a range of autoimmune mouse strains developed by the University as specified in any executed Work Order and Schedule 2

  Vinuesa, C. (PI), Ellyard, J. (CoI) & Lorenzo, A. M. (CoI)

  29/09/21 → 31/12/24

  Project: Research

  • Idronoxil 100%
  • Mouse Strain 50%

• EVEREST study: Evaluation of COVID-19 Vaccination Efficacy and Rare Events in Solid Tumours

  Kanjanapan, Y. (PI), Almonte, A. (CoI), Cavic, G. (CoI), Choi, P. (CoI), Cockburn, I. (CoI), Fahrer, A. (CoI), Gardiner, E. (CoI), Hicks, S. (CoI), Neeman, T. (CoI) & Yip, D. (CoI)

  1/08/21 → 31/03/22

  Project: Research

  • Vaccine Immunogenicity 100%

• Understanding how heparan sulfate mimetics control neuroinflammation

  Bruestle, A. (PI), La Flamme, A. C. (PI), Parish, C. (CoI) & Zubkova, O. (CoI)

  1/08/21 → 31/07/24

  Project: Research

  • Nervous System Inflammation 100%
  • Heparan Sulfate 100%

• Missed opportunities in clinical practice: Tools to enhance clinician awareness and diagnosis of rare diseases in Australia

  Desborough, J. (PI), Cook, M. (CoI), Parkinson, A. (CoI) & Phillips, C. (CoI)

  1/07/21 → 31/01/24

  Project: Research

• Discovery of drugs suitable for the treatment of Waldenstrm Macroglobulinemia

  Talaulikar, D. (PI) & Man, S. M. (CoI)

  1/07/21 → 12/10/23

  Project: Research