Research output per year
Research output per year
Personal profile
Research student supervision
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Dive into the research topics where Adele Lehane is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Optimization and Characterization of N-Acetamide Indoles as Antimalarials That Target PfATP4
Awalt, J. K., Ooi, Z. K., Ashton, T. D., Mansouri, M., Calic, P. P. S., Zhou, Q., Vasanthan, S., Lee, S., Loi, K., Jarman, K. E., Penington, J. S., Qiu, D., Zhang, X., Lehane, A. M., Mao, E. Y., Gancheva, M. R., Wilson, D. W., Giannangelo, C., MacRaild, C. A. & Creek, D. J. & 21 others, , 24 Apr 2025, In: Journal of Medicinal Chemistry. 68, 8, p. 8933-8966 34 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A pH Fingerprint Assay to Identify Inhibitors of Multiple Validated and Potential Antimalarial Drug Targets
Lindblom, J. C. R., Zhang, X. & Lehane, A. M., 18 Mar 2024, In: ACS Infectious Diseases. 10, 4, p. 1185-1200 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (SciVal) -
Discovery of antiplasmodial pyridine carboxamides and thiocarboxamides
Redway, A., Spry, C., Brown, A., Wiedemann, U., Fathoni, I., Garnie, L. F., Qiu, D., Egan, T. J., Lehane, A. M., Jackson, Y., Saliba, K. J. & Downer-Riley, N., Aug 2024, In: International Journal for Parasitology: Drugs and Drug Resistance. 25, 100536.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (SciVal) -
Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4
Ashton, T. D., Calic, P. P. S., Dans, M. G., Kang Ooi, Z., Zhou, Q., Loi, K., Jarman, K. E., Palandri, J., Qiu, D., Lehane, A. M., Maity, B., De, N., Famodimu, M. T., Delves, M. J., Mao, E. Y., Gancheva, M. R., Wilson, D. W., Chowdury, M., de Koning-Ward, T. F. & Baud, D. & 4 others, , 2024, In: ChemMedChem. 19, 24, 16 p., e202400549.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4
Ashton, T. D., Calic, P. P. S., Dans, M. G., Ooi, Z. K., Zhou, Q., Palandri, J., Loi, K., Jarman, K. E., Qiu, D., Lehane, A. M., Maity, B. C., De, N., Giannangelo, C., MacRaild, C. A., Creek, D. J., Mao, E. Y., Gancheva, M. R., Wilson, D. W., Chowdury, M. & de Koning-Ward, T. F. & 9 others, , 12 Aug 2024, In: Journal of Medicinal Chemistry. 67, 16, p. 14493-14523 31 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus)
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Na()-dysregulating antimalarials: blocking the roads to resistance by understanding PfATP4 and its place in parasite physiology
Lehane, A. (PI), Corry, B. (CoI), Fidock, D. A. (CoI), Kirk, K. (CoI), Sleebs, B. (CoI) & van Dooren, G. (CoI)
1/01/24 → 31/12/27
Project: Research
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How do apicomplexan parasites steal amino acids from their hosts?
van Dooren, G. (PI), Kirk, K. (CoI) & Lehane, A. (CoI)
1/01/23 → 31/12/25
Project: Research
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PfATP4 screening - A pH-based 'fingerprint' screen to simultaneously identify inhibitors of multiple validated and potential antimalarial drug targets
Lehane, A. (PI) & George, A. (CoI)
1/09/19 → 31/12/21
Project: Research
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Understanding high-level resistance to antimalarial PfATP4 inhibitors
Lehane, A. (PI) & Kirk, K. (CoI)
1/01/19 → 31/10/21
Project: Research
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