Personal profile
Biography
Immunology
Cancer Biology
Molecular Biology
Microbiology
Education/Academic qualification
Immunology and Cancer, PhD
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Dive into the research topics where Cheng Shen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Inflammasome protein scaffolds the DNA damage complex during tumor development
Shen, C., Pandey, A., Tuipulotu, D. E., Mathur, A., Liu, L., Yang, H., Adikari, N. K., Ngo, C., Jing, W., Feng, S., Hao, Y., Zhao, A., Kirkby, M., Kurera, M., Zhang, J., Venkataraman, S., Liu, C., Song, R., Wong, J. J.-L. & Schumann, U. & 5 others, , 14 Oct 2024, In: Nature Immunology. 25, 11, p. 2085-2096 35 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome
Pandey, A., Shen, C., Feng, S., Tuipulotu, D. E., Ngo, C., Liu, C., Kurera, M., Mathur, A., Venkataraman, S., Zhang, J., Talaulikar, D., Song, R., Wong, J. J. L., Teoh, N., Kaakoush, N. O. & Man, S. M., 26 Jan 2024, In: Science advances. 10, 4Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome
Mathur, A., Kay, C., Xue, Y., Pandey, A., Lee, J., Jing, W., Enosi Tuipulotu, D., Lo Pilato, J., Feng, S., Ngo, C., Zhao, A., Shen, C., Rug, M., Miosge, L. A., Atmosukarto, I. I., Price, J. D., Ali, S. A., Gardiner, E. E., Robertson, A. A. B. & Awad, M. M. & 3 others, , Apr 2023, In: EMBO Reports. 24, 6, 20 p., e54600.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (Scopus) -
Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes
Enosi Tuipulotu, D., Feng, S., Pandey, A., Zhao, A., Ngo, C., Mathur, A., Lee, J., Shen, C., Fox, D., Xue, Y., Kay, C., Kirkby, M., Lo Pilato, J., Kaakoush, N. O., Webb, D., Rug, M., Robertson, A. A. B., Tessema, M. B., Pang, S. & Degrandi, D. & 9 others, , 10 Feb 2023, In: EMBO Journal. 42, 6, p. e112558 e112558.Research output: Contribution to journal › Article › peer-review
Open Access30 Citations (Scopus) -
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins
Jing, W., Pilato, J. L., Kay, C., Feng, S., Tuipulotu, D. E., Mathur, A., Shen, C., Ngo, C., Zhao, A., Miosge, L. A., Ali, S. A., Gardiner, E. E., Awad, M. M., Lyras, D., Robertson, A. A. B., Kaakoush, N. O. & Man, S. M., May 2022, In: Science immunology. 7, 71, eabm1803.Research output: Contribution to journal › Article › peer-review
Open Access37 Citations (Scopus)