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Collaborations and top research areas from the last five years
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Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome
Fox, D., Mathur, A., Xue, Y., Liu, Y., Tan, W. H., Feng, S., Pandey, A., Ngo, C., Hayward, J. A., Atmosukarto, I. I., Price, J. D., Johnson, M. D., Jessberger, N., Robertson, A. A. B., Burgio, G., Tscharke, D. C., Fox, E. M., Leyton, D. L., Kaakoush, N. O. & Märtlbauer, E. & 2 others, , 1 Dec 2020, In: Nature Communications. 11, 1, 760.Research output: Contribution to journal › Article › peer-review
Open Access74 Citations (Scopus) -
Molecular basis for the folding of β-helical autotransporter passenger domains
Yuan, X., Johnson, M. D., Zhang, J., Lo, A. W., Schembri, M. A., Wijeyewickrema, L. C., Pike, R. N., Huysmans, G. H. M., Henderson, I. R. & Leyton, D. L., 1 Dec 2018, In: Nature Communications. 9, 1, 1395.Research output: Contribution to journal › Article › peer-review
Open Access24 Citations (Scopus) -
Of linkers and autochaperones: An unambiguous nomenclature to identify common and uncommon themes for autotransporter secretion
Drobnak, I., Braselmann, E., Chaney, J. L., Leyton, D. L., Bernstein, H. D., Lithgow, T., Luirink, J., Nataro, J. P. & Clark, P. L., 1 Jan 2015, In: Molecular Microbiology. 95, 1, p. 1-16 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access31 Citations (Scopus) -
The β-barrel assembly machinery complex
Leyton, D. L., Belousoff, M. J. & Lithgow, T., 1 Apr 2015, Methods in Molecular Biology. Humana Press Inc., (Methods in Molecular Biology; vol. 1329).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
11 Citations (Scopus) -
A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes
Leyton, D. L., Johnson, M. D., Thapa, R., Huysmans, G. H. M., Dunstan, R. A., Celik, N., Shen, H. H., Loo, D., Belousoff, M. J., Purcell, A. W., Henderson, I. R., Beddoe, T., Rossjohn, J., Martin, L. L., Strugnell, R. A. & Lithgow, T., 26 Jun 2014, In: Nature Communications. 5, 4239.Research output: Contribution to journal › Article › peer-review
Open Access42 Citations (Scopus)
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Targeting an essential bridge between bacterial membranes
Doyle, M. (PI), Leyton, D. (PI), Bernstein, H. (CoI) & North, R. (CoI)
19/02/26 → 28/02/29
Project: Research
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Development of a delivery system for the targeted release of nanobodies in the gut
Leyton, D. (PI)
1/01/26 → 31/12/28
Project: Research
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A robotics platform for structural biology
Jackson, C. (PI), Carver, J. (CoI), Leyton, D. (CoI), Pogson, B. (CoI) & Williams, S. (CoI)
10/04/18 → 31/12/18
Project: Research
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Dissecting the pathogenic triad of enteric pathogens: Assembly, structure and function of autotransporter proteases
Heras, B. (PI), Leyton, D. (PI), Pike, R. (CoI) & Wijeyewickrema, L. (CoI)
1/01/18 → 31/12/22
Project: Research
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Fast liquid chromatography system for purification of protein and peptides
Williams, S. (PI), Callaghan, R. (CoI), Leyton, D. (CoI), Solomon, P. (CoI) & Spry, C. (CoI)
6/04/17 → 31/12/17
Project: Research