Personal profile
Biography
Eduardo Eyras is an EMBL Australia Group Leader and Professor at the Australian National University (ANU), where he develops computational methods to study transcriptomes and epitranscriptomes and their alterations in cancer using long-read sequencing technologies. Before joining ANU, Eduardo Eyras worked at the Sanger Institute (2001-2004) and was group leader at the Pompeu Fabra University in Barcelona, Spain (2005-2019). During this time, he developed methods to annotate RNA alternative splicing in genomes, contributed to the landmark analyses of the human, mouse, rat, chicken, and cow genomes, and led a research program on Machine Learning applied to RNA biology and cancer.
External Scholarly Memberships and Affiliations
ARC College of Experts, Australian Research Council
Research student supervision
- Registered to supervise
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Collaborations and top research areas from the last five years
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Biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing with RISER
Sneddon, A., Ravindran, A., Shanmuganandam, S., Kanchi, M., Hein, N., Jiang, S., Shirokikh, N. & Eyras, E., 24 May 2024, In: Nature Communications. 15, 17 p., 4422.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Comprehensive translational profiling and STE AI uncover rapid control of protein biosynthesis during cell stress
Horvath, A., Janapala, Y., Woodward, K., Mahmud, S., Cleynen, A., Gardiner, E. E., Hannan, R. D., Eyras, E., Preiss, T. & Shirokikh, N. E., 22 Jul 2024, In: Nucleic Acids Research. 52, 13, p. 7925–7946 22 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells
Velasco-Hernandez, T., Trincado, J. L., Vinyoles, M., Closa, A., Martínez-Moreno, A., Gutiérrez-Agüera, F., Molina, O., Rodríguez-Cortez, V. C., Ximeno-Parpal, P., Fernández-Fuentes, N., Petazzi, P., Beneyto-Calabuig, S., Velten, L., Romecin, P., Casquero, R., Abollo-Jiménez, F., de la Guardia, R. D., Lorden, P., Bataller, A. & Lapillonne, H. & 9 others, , 26 Feb 2024, In: HemaSphere. 8, 2, 16 p., e45.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications
Mateos, P. A., Sethi, A. J., Ravindran, A., Srivastava, A., Woodward, K., Mahmud, S., Kanchi, M., Guarnacci, M., Xu, J., Yuen, Z. W. S., Zhou, Y., Sneddon, A., Hamilton, W., Gao, J., Starrs, L. M., Hayashi, R., Wickramasinghe, V., Zarnack, K., Preiss, T. & Burgio, G. & 3 others, , 9 May 2024, In: Nature Communications. 15, 17 p., 3899.Research output: Contribution to journal › Article › peer-review
65 Citations (Scopus) -
Profiling age and body fluid DNA methylation markers using nanopore adaptive sampling
Yuen, Z. W. S., Shanmuganandam, S., Stanley, M., Jiang, S., Hein, N., Daniel, R., McNevin, D., Jack, C. & Eyras, E., Jul 2024, In: Forensic Science International: Genetics. 71, 10 p., 103048.Research output: Contribution to journal › Article › peer-review
Open Access21 Citations (Scopus)
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The Evolutionary Landscape of RNA Modification in Mammals
Eyras, E. (PI), Weatheritt, R. (PI) & Shirokikh, N. (CoI)
18/03/26 → 17/03/29
Project: Research
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ARC Centre of Excellence for the Mathematical Analysis of Cellular Systems
Stumpf, M. (PI), Wen, J. (PI), Beilharz, T. (CoI), Coster, A. (CoI), Eyras, E. (CoI), Flegg, J. (CoI), Lithgow, T. (CoI), McConville, M. J. (CoI), McDonald, M. (CoI), Morris, R. (CoI), Nguyen, L. (CoI), Reid, G. (CoI), Shim, H. (CoI), Simpson, M. (CoI), Stone, E. (CoI), Wilkins, M. R. (CoI) & Zhang, W. (CoI)
9/02/24 → 8/02/31
Project: Research
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Accelerating messenger RNA (mRNA) therapeutics by cracking the epitranscriptomic code
Eyras, E. (PI)
1/01/23 → 31/12/26
Project: Research
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Identifying the intracellular localisation and isoforms of up to five lncTNBC in Triple-Negative Breast Cancer
Preiss, T. (PI), Eyras, E. (CoI), Janapala, Y. (CoI), Rana, Z. (CoI), Ravindran, A. (CoI) & Sneddon, A. (CoI)
15/05/24 → 14/08/24
Project: Research
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Evaluation of CSIROs technology for RNA innovation
Eyras, E. (PI) & Burgio, G. (CoI)
1/07/23 → 31/03/25
Project: Research