Dr. Hyungtaek Jung has joined the ANU College of Health and Medicine, specifically the National Centre for Indigenous Genomics (https://ncig.anu.edu.au/), with the primary objective of supporting life scientists in analysing extensive biological data produced through cutting-edge sequencing technologies. His mission involves overcoming the current limitations of human reference genomes (GRCh38 and T2T-CHM13) by creating comprehensive genomic resources tailored to the Indigenous Australian population. This includes:

1. Generating haplotype-resolved telomere-to-telomere (T2T) Indigenous genomes.
2. Compiling a thorough catalogue of genetic variations anchored to Indigenous-T2T genomes.
3. Facilitating clinical genomics applications for Indigenous communities.

Dr. Jung brings with him a wealth of successful experience collaborating with diverse national and international laboratories. His expertise spans various fields, including life and clinical sciences, aquaculture and agriculture, molecular ecology, genomics, and bioinformatics.

1. Genomics and Bioinformatics
2. Telomere-to-Telomere Genomes
3. Pan-Genomes and Transcriptomes (Including Gene Expression)
4. Molecular Evolution and Comparative Genomics
5. Genome Structure and Regulation (Including Structural Variation and Epigenetics)

Genomics and Bioinformatics Focus:

• Proficiency in Advanced Genome and Transcriptome Assembly and Annotation Techniques
• Utilisation of Cutting-edge Approaches for Methylation and Epigenomics Studies
• Specialisation in T2T and PanGenome Research
  • Attainment of T2T Genome Assemblies through Overlap, de Bruijn Graphs, and K-mer Methods
  • Pioneering T2T-PanGenome Research for Human Genomic Studies and Australian Indigenous Populations
• Expertise in Comparative and Functional Genomics Research
  • Exploration of Structural Variations in Genome Evolution and Functional Diversity
  • Investigation of Gene/Genome Duplication and Rearrangement
• Proficient in Genome Browsers and Analytical Pipelines
  • Development and curation of dynamic web interfaces for comprehensive genome examination
  • Implementation of nextflow and snakemake applications for large-scale analysis

Computational and Digital Biology Applications

• Application of Computational Biology in Personalised Medicine
• Integration of SMART farming solutions through computational and digital biology approaches