Research output per year
Research output per year
Personal profile
Biography
Professor Hannan is an internationally recognised laboratory scientist, whose work on ribosome biogenesis has led to new treatment paradigms in cancer, centred on drugs that activate nucleolar stress. He received his PhD from the University of Tasmania in 1994, before undertaking postdoctoral research in the USA. Since returning to Australia in 2000, he has held prominent positions at the Baker Medical Research Institute and the Peter MacCallum Cancer Centre in Melbourne. Recently Ross brought together multi-disciplinary teams of laboratory and clinician researchers, and forged industry collaborations to devise ‘first in class’ RNA polymerase I inhibitors, that are now in clinical trial for a range of heamatologic cancers. Hannan’s far-reaching contributions were recognised in his recent appointment as inaugural Centenary Chair in Cancer Research and Head of the ACRF Department of Cancer Biology and Therapeutics at John Curtin School of Medical Research, ANU.
Qualifications
BSc (Hons) PhD FAHMS
Research Interests
Cancer Biology
Cancer Therapeutics
Transcription
Chromatin and Epigenetics
Ribosome Biogenesis
High Throughput Functional Screening
Genomics
External Scholarly Memberships and Affiliations
Honorary Member , Advisory Council, European Association for Cancer Research
2018 → …
Australia Node Leader, European Molecular Biology Laboratory
2017 → …
Adjunct Professor, Peter Maccallum Cancer Centre
2015 → …
Adjunct Professor, School of Biological Sciences, University of Queensland
2015 → …
2012- Adjunct Professor, Department of Biochemistry and Molecular Biology, The Monash Biomedicine Discovery Institute, Monash University
2012 → …
Adjunct Professor, Department of Biochemistry and Molecular Biology, University of Melbourne
2012 → …
Member, European Association for Cancer Research
2004 → …
Member, National Association of Research Fellows
2002 → …
President, Australian Society for Biochemistry and Molecular Biology (ASBMB)
2000 → …
Member, High Blood Pressure Research Council of Australia
1999 → …
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Collaborations and top research areas from the last five years
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Comprehensive translational profiling and STE AI uncover rapid control of protein biosynthesis during cell stress
Horvath, A., Janapala, Y., Woodward, K., Mahmud, S., Cleynen, A., Gardiner, E. E., Hannan, R. D., Eyras, E., Preiss, T. & Shirokikh, N. E., 22 Jul 2024, In: Nucleic Acids Research. 52, 13, p. 7925–7946 22 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting the ribosome to treat multiple myeloma
Maclachlan, K. H., Gitareja, K., Kang, J., Cuddihy, A., Yuxi, C., Hein, N., Cullinane, C., Ang, C. S., Brajanovski, N., Pearson, R. B., Khot, A., Sanij, E., Hannan, R., Poortinga, G. & J. Harrison, S., 21 Mar 2024, In: Molecular Therapy: Oncology. 32, 1, 200771.Research output: Contribution to journal › Article › peer-review
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Cell death and barrier disruption by clinically used iodine concentrations
Steins, A., Carroll, C., Choong, F. J., George, A. J., He, J. S., Parsons, K. M., Feng, S., Man, S. M., Kam, C., van Loon, L. M., Poh, P., Ferreira, R., Mann, G. J., Gruen, R. L., Hannan, K. M., Hannan, R. D. & Schulte, K. M., 2023, In: Life Science Alliance. 6, 6, e202201875.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Psi promotes Drosophila wing growth via direct transcriptional activation of cell cycle targets and repression of growth inhibitors
Zaytseva, O., Mitchell, N. C., Muckle, D., Delandre, C., Nie, Z., Werner, J. K., Lis, J. T., Eyras, E., Hannan, R. D., Levens, D. L., Marshall, O. J. & Quinn, L. M., 24 Jan 2023, In: Development (Cambridge). 150, 2, dev201563.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting mutant dicer tumorigenesis in pleuropulmonary blastoma via inhibition of RNA polymerase I
Wong, M. R. E., Lim, K. H., Hee, E. X. Y., Chen, H., Kuick, C. H., Aw, S. J., Chang, K. T. E., Syed Sulaiman, N., Low, S. YY., Hartono, S., Tran, A. N. T., Ahamed, S. H., Lam, C. M. J., Soh, S. Y., Hannan, K. M., Hannan, R. D., Coupland, L. A. & Loh, A. H. P., Aug 2023, In: Translational Research. 258, p. 60-71 12 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)
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iLAuNCH - Manufacturing wearable-based health solutions for space medicine SC-3
Schulte, K., Gruen, R., Hannan, R., Moore, A., Smart, T. & van Loon, L. M.
Australian National University (ANU), Commonwealth Department of Education (Formerly DESE)
1/04/24 → 30/09/26
Project: Research
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PMR-116, a novel inhibitor of ribosome biogenesis with antitumor activity in preclinical models of prostate cancer
Hannan, R., Furic, L. & Hannan, K.
15/09/22 → 14/09/25
Project: Research
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Establishing the Canberra Brain Cancer Collaborative to connect patients with research, drug discovery and clinical trials
Quinn, L., Eyras, E., Gilbert, M., Gomez, G., Hannan, R., Hindson, C., Mamalai, S., Mews, P. J., Nisbet, D., Pranavan, G. & Syed, F.
1/03/22 → 28/02/25
Project: Research
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How novel ribosomal RNA gene repeat variants drive cellular function
Eyras, E., Ganley, A. R. D., Hannan, R., Hein, N., Lin, Y. & Preiss, T.
1/01/22 → 31/12/24
Project: Research