Personal profile
Biography
Simon completed his undergraduate medical training at the University of Newcastle and specialist training in Nephrology at The Canberra and Royal Prince Alfred Hospitals. He received his Masters in Medicine(Hons) from the University of Sydney and his PhD at the ANU as an NHMRC/RACP scholar investigating the role of genetic variation in systemic lupus erythematosus.
Simon’s laboratory investigates the genetic and molecular mechanisms of systemic autoimmunity and kidney disease. He leads a national translational personalised medicine program centred at The Canberra Hospital and ANU which investigates complex autoimmunity by identifying potential pathogenic gene variants and demonstrating the molecular and immune consequence of these variants. In collaboration with the National Centre for Indigenous Genomics, he also uses this personalised medicine approach to investigate the unique genetic basis of kidney disease in Indigenous Australians.
Qualifications
BMed MMed(Hons) FRACP PhD
Research student supervision
- Registered to supervise
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Collaborations and top research areas from the last five years
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Advanced immunophenotyping of lymphocyte and monocyte subsets in healthy Australian adults using a novel spectral flow cytometry panel
Davies, A. R., Kwong, K., Yu, Z., Diamand, K. E. M., Li, F.-J., Kannitha, L., Ali, S. A., Amjadipour, A., Padarin, A.-M., Devoy, M., Vohra, H., Miraghazadeh, B., Jiang, S. H., Brüstle, A., Cherbuin, N., Nolan, C. J., Cook, M. C., Gardiner, E. E., Read, S. & McNaughton, E. & 1 others, , 22 Jul 2025, In: Frontiers in Immunology. Volume 16 - 2025, 22 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A TNIP1-driven systemic autoimmune disorder with elevated IgG4
Medhavy, A., Athanasopoulos, V., Bassett, K., He, Y., Stanley, M., Enosi Tuipulotu, D., Cappello, J., Brown, G. J., Gonzalez-Figueroa, P., Turnbull, C., Shanmuganandam, S., Tummala, P., Hart, G., Lea-Henry, T., Wang, H., Nambadan, S., Shen, Q., Roco, J. A., Burgio, G. & Wu, P. & 11 others, , Sept 2024, In: Nature Immunology. 25, 9, p. 1678-1691 14 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
Biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing with RISER
Sneddon, A., Ravindran, A., Shanmuganandam, S., Kanchi, M., Hein, N., Jiang, S., Shirokikh, N. & Eyras, E., 24 May 2024, In: Nature Communications. 15, 17 p., 4422.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Dynamic survival prediction of end-stage kidney disease using random survival forests for competing risk analysis
Christiadi, D., Chai, K., Chuah, A., Loong, B., D. Andrews, T., Chakera, A., Walters, G. D. & Jiang, S. H. T., 2024, In: Frontiers in Medicine. 11, 1428073.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Profiling age and body fluid DNA methylation markers using nanopore adaptive sampling
Yuen, Z. W. S., Shanmuganandam, S., Stanley, M., Jiang, S., Hein, N., Daniel, R., McNevin, D., Jack, C. & Eyras, E., Jul 2024, In: Forensic Science International: Genetics. 71, 10 p., 103048.Research output: Contribution to journal › Article › peer-review
Open Access21 Citations (Scopus)
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Resolving how A20 variants drive toll-like receptor mediated kidney disease in Indigenous Australians
Athanasopoulos, V. (PI), Downes, M. (CoI), Hermes, A. (CoI), Jiang, S. (CoI), Lea-Henry, T. (CoI), McMorran, B. (CoI) & Nolan, C. (CoI)
1/01/26 → 31/12/29
Project: Research
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Improving genetic diagnosis of autoimmune and autoinflammatory disease through an integrated multi-omics approach
Jiang, S. (PI), Alexander, S. (CoI), Alexander, S. (CoI), Andrews, D. (CoI), Ascher, D. (CoI), Ascher, D. (CoI), Athanasopoulos, V. (CoI), Chakera, A. (CoI), Day, J. (CoI), Morrisroe, K. (CoI), Nikpour, M. (CoI), Randall, K. (CoI), Wicks, I. (CoI) & Yu, D. (CoI)
1/06/23 → 31/05/27
Project: Research
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Personalised medicine in the treatment of complex autoimmunity and autoinflammatory disease
Jiang, S. (PI), Andrews, D. (CoI), Athanasopoulos, V. (CoI), Chakera, A. (CoI), Morrisroe, K. (CoI), Randall, K. (CoI), Rogers, N. (CoI), Rogers, N. (CoI) & Walters, G. (CoI)
1/02/23 → 31/01/27
Project: Research
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Kidney Disease in the Tiwi people
McMorran, B. (PI), Easteal, S. (CoI), Hermes, A. (CoI), Jiang, S. (CoI) & Patel, H. (CoI)
1/01/20 → 31/12/26
Project: Research
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Comprehensive Immunophenotyping to identify novel treatment targets in refractory autoimmune kidney disease
Jiang, S. (PI)
11/01/24 → 31/07/25
Project: Research