Research output per year
Research output per year
Personal profile
Biography
Zaka Yuen is a Postdoc in Prof. Eduardo Eyras's lab at the Australian National University (ANU), working in collaboration with Dr. Nadine Hein. Zaka specializes in computational biology and long-read sequencing technologies.
During her PhD in the same lab, she benchmarked nanopore methylation tools and explored PCR-free nanopore targeting techniques, including Cas9 enrichment and adaptive sampling. Her PhD research involved the bioinformatic analysis of nanopore signal data, particularly in DNA methylation studies, where she developed bioinformatic pipelines.
In a follow-up project, Zaka identified DNA methylation markers specific to age and body fluid using nanopore sequencing for forensic science applications. Currently, her research focuses on investigating ribosomal DNA repeats in cancer progression using long-read sequencing.
Education/Academic qualification
Doctor of Philosophy, Targeted nanopore sequencing for forensic SNP genotyping and CpG methylation profiling, The Australian National University
Award Date: 13 Dec 2023
Forensic genetics, Honours, Improving the end graphical user interface of a forensic bioinformatics pipeline, University of Canberra
Award Date: 25 Sept 2018
Fingerprint
Dive into the research topics where Zaka Yuen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Find out about recent ANU collaborations across the world by selecting a location on the map OR
Research output
- 3 Article
-
Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications
Mateos, P. A., Sethi, A. J., Ravindran, A., Srivastava, A., Woodward, K., Mahmud, S., Kanchi, M., Guarnacci, M., Xu, J., Yuen, Z. W. S., Zhou, Y., Sneddon, A., Hamilton, W., Gao, J., Starrs, L. M., Hayashi, R., Wickramasinghe, V., Zarnack, K., Preiss, T., Burgio, G., & 3 others, 9 May 2024, In: Nature Communications. 15, 17 p., 3899.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Profiling age and body fluid DNA methylation markers using nanopore adaptive sampling
Yuen, Z. W. S., Shanmuganandam, S., Stanley, M., Jiang, S., Hein, N., Daniel, R., McNevin, D., Jack, C. & Eyras, E., Jul 2024, In: Forensic Science International: Genetics. 71, 10 p., 103048.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing
Yuen, Z. W. S., Srivastava, A., Daniel, R., McNevin, D., Jack, C. & Eyras, E., 1 Dec 2021, In: Nature Communications. 12, 1, 3438.Research output: Contribution to journal › Article › peer-review
Open Access81 Citations (Scopus)