Control of translation in cancer, cell stress response and ageing

To fight ageing and cancer, we need to understand the mechanisms underlying adaptation of our cells to damaging stresses. Our DNA encodes proteins that enable cells to effectively cope with stress, but these must be produced rapidly and at the right time and amount. This project will unravel mechanisms of frontline stress responses with pioneering detail. It will provide knowledge and methods helping to detect, enhance or suppress fast adaptation of human cells, to apply in industry and health.