Follicular cytotoxic T cell differentiation and function in infection and B-cell lymphoma

  • Yu, Di (PI)

    Project: Research

    Project Details

    Description

    Cytotoxic T cells eliminate infected or cancerous cells, constituting a major arm of the immune defence. In this study, we will investigate a subset of cytotoxic T cells that particularly migrate into B cell follicles to control infection and malignancy. Understanding of the differentiation and function of this subset, termed as follicular cytotoxic T (TFC) cells, will help us to develop new strategies to treat EBV and HIV infectionsas well as B cell lymphomas.
    StatusFinished
    Effective start/end date1/01/1831/12/19

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