Generation and exploitation of novel fermentation products in the synthesis of biologically active organic compounds with therapeutic potential

  • Banwell, Martin (PI)

    Project: Research

    Project Details

    Description

    This project seeks to establish, using novel combinations of chemical, molecular biological, microbiological and fermentation techniques, efficient total syntheses of certain classes of biologically active natural products and their analogues. Through this integrated approach, concise routes to rare natural products possessing unusual structures will emerge and thereby allowing for a comprehensive assessment of their value as potential therapeutic agents. Specifically targetted compounds include alkaloids, terpenoids and polyketide natural products displaying significant antibacterial, antifungal, cytotoxic, and/or reversal of multidrug resistance properties.
    StatusFinished
    Effective start/end date1/01/1231/12/15

    Fingerprint

    Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.