Project Details
Description
This project seeks to establish, using novel combinations of chemical, molecular biological, microbiological and fermentation techniques, efficient total syntheses of certain classes of biologically active natural products and their analogues. Through this integrated approach, concise routes to rare natural products possessing unusual structures will emerge and thereby allowing for a comprehensive assessment of their value as potential therapeutic agents. Specifically targetted compounds include alkaloids, terpenoids and polyketide natural products displaying significant antibacterial, antifungal, cytotoxic, and/or reversal of multidrug resistance properties.
Status | Finished |
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Effective start/end date | 1/01/12 → 31/12/15 |
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