MS Australia Senior Fellowship: Utilising the innate immune system to improve monitoring and treatment development in Multiple Sclerosis

Most research into the autoimmune component of MS and most therapeutic interventions have focused on T- and B- cells, the main cells in the adaptive immune responses. However, the other less well explored side of the immune system the innate immune system is emerging as potent player in the context of MS. We here investigate the abundance and function of two major innate cell populations using the experimental autoimmune encephalomyelitis (EAE) model an array of state-of-the-art flowcytometric technics as well as single cell RNA seq.