Myelin Plasticity - How Does it Work?

Oligodendrocytes are cells in the central nervous system that increase the speed and reliability of informationtransfer, enabling the development of more complex nervous systems. It was recently discovered that newoligodendrocytes are continually added to the brain throughout life (myelin plasticity) that needed for learning.However we do not understand how this process works. This project aims to uncover how oligodendrocytesmodify brain circuits and characterize the molecular mediators of this process. This new knowledge will elucidate the cellular mechanisms that allow the nervous system to remain adaptable throughout life.