Predicting Renal, Ophthalmic and Heart Events in the Aboriginal Community: The PROPHECY Diabetes Multi-Omics Cohort Study

  • Brown, Alex (PI)
  • Cooper, Mark (CoI)
  • Craig, Jamie E (CoI)
  • El-Osta, Sam (CoI)
  • James, David (CoI)
  • Kovacic, Jason (CoI)
  • Maple-Brown, L. J. (CoI)
  • Nicholls, Stephen (CoI)
  • Shaw, Jonathan (CoI)
  • Willerslev, Eske (CoI)
  • Zimmet, Paul (CoI)

    Project: Research

    Project Details

    Description

    Type 2 Diabetes (T2D) is at epidemic proportions in Indigenous Australians, affecting up to 50% of adults over the age of 50. T2D significantly impairs the quality and length of life and contributes to wide life expectancy differentials. Much of this inequality is a consequence of the rapid development of renal, cardiovascular, and ophthalmological complications. In partnership with Aboriginal communities and health organisations, and world-leading experts in T2D and genomics, we have established a large population-based prospective cohort of Aboriginal adults from across the breadth of South Australia. Our fundamental objective is to better understand the burden, natural history and propensity for complication development in Aboriginal people with or at risk of T2D; specifically, outlining the social, psychological, environmental, clinical and genomic predictors of disease and disease progression.
    StatusActive
    Effective start/end date1/01/2230/09/25

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