Targeting a novel epigenetic regulator of Hodgkin lymphoma, H2A.B, for treament of cancer

  • Soboleva, Tatiana (PI)
  • Sobolev, Alexander S (CoI)

    Project: Research

    Project Details

    Description

    We have identified a novel key regulator of Hodgkin Lymphoma, epigenetic factor, histone H2A.B. This proposal aims to develop novel therapeutic tools that would target H2A.B and potentially provide a more specific and less toxic treatment for Hodgkin Lymphoma patients. We will use Modular Nanotransporters, a highly specific intracellular delivery system, to target H2A.B for degradation and we will use the small molecule kinase inhibitors for functional inactivation of H2A.B.
    StatusActive
    Effective start/end date1/01/2231/12/25

    Funding

    • National Health and Medical Research Council (NHMRC): A$1,041,339.00

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