Understanding ion conduction and drug binding in voltage gated sodium channels

    Project: Research

    Project Details

    Description

    Many local anaesthetic, anti-epileptic and anti-arrythmic drugs act by targeting the proteins that initiate electrical impulses in nerve and muscle. This project will use new information about the shape of these proteins to understand the mode of drug action and to aid the future design of more tailored therapeutics with fewer side effects.
    StatusFinished
    Effective start/end date10/02/1422/09/20

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