3D Silicon Microdosimetry and RBE Study Using {12}{rm C} Ion of Different Energies

Linh T. Tran; Lachlan Chartier; David Bolst; Dale A. Prokopovich; Susanna Guatelli; Michell Nancarrow; Mark I. Reinhard; Marco Petasecca; Michael L.F. Lerch; Vladimir L. Pereverlaylo; Naruhiro Matsufuji; David Hinde; Mahananda Dasgupta; Andrew Stuchbery; Michael Jackson; Anatoly B. Rosenfeld

doi:10.1109/TNS.2015.2487266

3D Silicon Microdosimetry and RBE Study Using {12}{rm C} Ion of Different Energies

Linh T. Tran, Lachlan Chartier, David Bolst, Dale A. Prokopovich, Susanna Guatelli, Michell Nancarrow, Mark I. Reinhard, Marco Petasecca, Michael L.F. Lerch, Vladimir L. Pereverlaylo, Naruhiro Matsufuji, David Hinde, Mahananda Dasgupta, Andrew Stuchbery, Michael Jackson, Anatoly B. Rosenfeld

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

This paper presents a new version of the 3D mesa Bridge microdosimeter comprised of an array of 4248 silicon cells fabricated on 10 thick n-type silicon-on-insulator substrate. This microdosimeter has been designed to overcome limitations existing in previous generation silicon microdosimeters and it provides well-defined sensitive volumes and high spatial resolution. The charge collection characteristics of the new 3D mesa microdosimeter were investigated using the ANSTO heavy ion microprobe, utilizing ions. Measurement of microdosimetric quantities allowed for the determination of the relative biological effectiveness of 290 MeV/u and 350heavy ion therapy beams at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. The microdosimetric RBE obtained showed good agreement with the tissue-equivalent proportional counter. Utilizing the high spatial resolution of the SOI microdosimeter, the LET spectra for 70MeV ions, like those present at the distal edge of 290 and 350 MeV/u beams, were obtained as the ions passed through thin layers of polyethylene film. This microdosimeter can provide useful information about the lineal energy transfer (LET) spectra downstream of the protective layers used for shielding of electronic devices for single event upset prediction.

Original language	English
Article number	7348797
Pages (from-to)	3027-3033
Number of pages	7
Journal	IEEE Transactions on Nuclear Science
Volume	62
Issue number	6
DOIs	https://doi.org/10.1109/TNS.2015.2487266
Publication status	Published - Dec 2015

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Tran, L. T., Chartier, L., Bolst, D., Prokopovich, D. A., Guatelli, S., Nancarrow, M., Reinhard, M. I., Petasecca, M., Lerch, M. L. F., Pereverlaylo, V. L., Matsufuji, N., Hinde, D., Dasgupta, M., Stuchbery, A., Jackson, M., & Rosenfeld, A. B. (2015). 3D Silicon Microdosimetry and RBE Study Using {12}{rm C} Ion of Different Energies. IEEE Transactions on Nuclear Science, 62(6), 3027-3033. Article 7348797. https://doi.org/10.1109/TNS.2015.2487266

@article{f085d3340e1640ceb51d09b7cc128ff3,

title = "3D Silicon Microdosimetry and RBE Study Using {12}{rm C} Ion of Different Energies",

abstract = "This paper presents a new version of the 3D mesa Bridge microdosimeter comprised of an array of 4248 silicon cells fabricated on 10 thick n-type silicon-on-insulator substrate. This microdosimeter has been designed to overcome limitations existing in previous generation silicon microdosimeters and it provides well-defined sensitive volumes and high spatial resolution. The charge collection characteristics of the new 3D mesa microdosimeter were investigated using the ANSTO heavy ion microprobe, utilizing ions. Measurement of microdosimetric quantities allowed for the determination of the relative biological effectiveness of 290 MeV/u and 350heavy ion therapy beams at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. The microdosimetric RBE obtained showed good agreement with the tissue-equivalent proportional counter. Utilizing the high spatial resolution of the SOI microdosimeter, the LET spectra for 70MeV ions, like those present at the distal edge of 290 and 350 MeV/u beams, were obtained as the ions passed through thin layers of polyethylene film. This microdosimeter can provide useful information about the lineal energy transfer (LET) spectra downstream of the protective layers used for shielding of electronic devices for single event upset prediction.",

keywords = "3D mesa, Charge collection, IBIC, heavy ion therapy, microdosimetry, silicon microdosimeter, single event upset",

author = "Tran, {Linh T.} and Lachlan Chartier and David Bolst and Prokopovich, {Dale A.} and Susanna Guatelli and Michell Nancarrow and Reinhard, {Mark I.} and Marco Petasecca and Lerch, {Michael L.F.} and Pereverlaylo, {Vladimir L.} and Naruhiro Matsufuji and David Hinde and Mahananda Dasgupta and Andrew Stuchbery and Michael Jackson and Rosenfeld, {Anatoly B.}",

note = "Publisher Copyright: {\textcopyright} 1963-2012 IEEE.",

year = "2015",

month = dec,

doi = "10.1109/TNS.2015.2487266",

language = "English",

volume = "62",

pages = "3027--3033",

journal = "IEEE Transactions on Nuclear Science",

issn = "0018-9499",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

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Tran, LT, Chartier, L, Bolst, D, Prokopovich, DA, Guatelli, S, Nancarrow, M, Reinhard, MI, Petasecca, M, Lerch, MLF, Pereverlaylo, VL, Matsufuji, N, Hinde, D , Dasgupta, M, Stuchbery, A, Jackson, M & Rosenfeld, AB 2015, '3D Silicon Microdosimetry and RBE Study Using {12}{rm C} Ion of Different Energies', IEEE Transactions on Nuclear Science, vol. 62, no. 6, 7348797, pp. 3027-3033. https://doi.org/10.1109/TNS.2015.2487266

TY - JOUR

T1 - 3D Silicon Microdosimetry and RBE Study Using {12}{rm C} Ion of Different Energies

AU - Tran, Linh T.

AU - Chartier, Lachlan

AU - Bolst, David

AU - Prokopovich, Dale A.

AU - Guatelli, Susanna

AU - Nancarrow, Michell

AU - Reinhard, Mark I.

AU - Petasecca, Marco

AU - Lerch, Michael L.F.

AU - Pereverlaylo, Vladimir L.

AU - Matsufuji, Naruhiro

AU - Hinde, David

AU - Dasgupta, Mahananda

AU - Stuchbery, Andrew

AU - Jackson, Michael

AU - Rosenfeld, Anatoly B.

PY - 2015/12

Y1 - 2015/12

N2 - This paper presents a new version of the 3D mesa Bridge microdosimeter comprised of an array of 4248 silicon cells fabricated on 10 thick n-type silicon-on-insulator substrate. This microdosimeter has been designed to overcome limitations existing in previous generation silicon microdosimeters and it provides well-defined sensitive volumes and high spatial resolution. The charge collection characteristics of the new 3D mesa microdosimeter were investigated using the ANSTO heavy ion microprobe, utilizing ions. Measurement of microdosimetric quantities allowed for the determination of the relative biological effectiveness of 290 MeV/u and 350heavy ion therapy beams at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. The microdosimetric RBE obtained showed good agreement with the tissue-equivalent proportional counter. Utilizing the high spatial resolution of the SOI microdosimeter, the LET spectra for 70MeV ions, like those present at the distal edge of 290 and 350 MeV/u beams, were obtained as the ions passed through thin layers of polyethylene film. This microdosimeter can provide useful information about the lineal energy transfer (LET) spectra downstream of the protective layers used for shielding of electronic devices for single event upset prediction.

AB - This paper presents a new version of the 3D mesa Bridge microdosimeter comprised of an array of 4248 silicon cells fabricated on 10 thick n-type silicon-on-insulator substrate. This microdosimeter has been designed to overcome limitations existing in previous generation silicon microdosimeters and it provides well-defined sensitive volumes and high spatial resolution. The charge collection characteristics of the new 3D mesa microdosimeter were investigated using the ANSTO heavy ion microprobe, utilizing ions. Measurement of microdosimetric quantities allowed for the determination of the relative biological effectiveness of 290 MeV/u and 350heavy ion therapy beams at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. The microdosimetric RBE obtained showed good agreement with the tissue-equivalent proportional counter. Utilizing the high spatial resolution of the SOI microdosimeter, the LET spectra for 70MeV ions, like those present at the distal edge of 290 and 350 MeV/u beams, were obtained as the ions passed through thin layers of polyethylene film. This microdosimeter can provide useful information about the lineal energy transfer (LET) spectra downstream of the protective layers used for shielding of electronic devices for single event upset prediction.

KW - 3D mesa

KW - Charge collection

KW - IBIC

KW - heavy ion therapy

KW - microdosimetry

KW - silicon microdosimeter

KW - single event upset

UR - http://www.scopus.com/inward/record.url?scp=84961828692&partnerID=8YFLogxK

U2 - 10.1109/TNS.2015.2487266

DO - 10.1109/TNS.2015.2487266

M3 - Article

SN - 0018-9499

VL - 62

SP - 3027

EP - 3033

JO - IEEE Transactions on Nuclear Science

JF - IEEE Transactions on Nuclear Science

IS - 6

M1 - 7348797

ER -

3D Silicon Microdosimetry and RBE Study Using {12}{rm C} Ion of Different Energies

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