TY - GEN
T1 - 670nm - A stop sign for retinal degenerations?
AU - Valter, K.
AU - Albarracin, R.
AU - Natoli, R.
AU - Rutar, M.
AU - Provis, J.
N1 - Publisher Copyright:
© Medimond.
PY - 2014
Y1 - 2014
N2 - This article presents a review of the work conducted in our laboratories using the 670nm light to test its efficacy in preventing or slowing the progression of retinal degeneration in the rodent retinal light-damage model. Using this model as an archetype of dry age-related macular degeneration we propose that 670nm light could be a viable option in the treatment of human AMD. We have found that irradiation of the eye with the 670nm light, using LED light arrays showed beneficial effects in photoreceptor survival1, 2, vascular development3 and moderating glial activation4 in a variety of rodent models. Based on these findings, we believe that photobiomodulation with 670nm red light has a great potential in retinal therapeutics, providing a non-invasive, and cost-effective treatment in retinal injury and degenerative conditions.
AB - This article presents a review of the work conducted in our laboratories using the 670nm light to test its efficacy in preventing or slowing the progression of retinal degeneration in the rodent retinal light-damage model. Using this model as an archetype of dry age-related macular degeneration we propose that 670nm light could be a viable option in the treatment of human AMD. We have found that irradiation of the eye with the 670nm light, using LED light arrays showed beneficial effects in photoreceptor survival1, 2, vascular development3 and moderating glial activation4 in a variety of rodent models. Based on these findings, we believe that photobiomodulation with 670nm red light has a great potential in retinal therapeutics, providing a non-invasive, and cost-effective treatment in retinal injury and degenerative conditions.
UR - http://www.scopus.com/inward/record.url?scp=84962822326&partnerID=8YFLogxK
M3 - Conference contribution
T3 - Proceedings of the WALT Biennial Congress and NAALT Annual Conference
SP - 33
EP - 38
BT - Proceedings of the WALT Biennial Congress and NAALT Annual Conference
A2 - Laakso, E.-Liisa
PB - MEDIMOND s.r.l.
T2 - 2014 WALT Biennial Congress and NAALT Annual Conference
Y2 - 9 September 2014 through 12 September 2014
ER -