A chemoenzymatic synthesis of the 12-membered macrolide (-)-cladospolide A

M. G. Banwell*, K. A. Jolliffe, D. T.J. Loong, K. J. McRae, F. Vounatsos

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    28 Citations (Scopus)

    Abstract

    The enantiomerically pure cis-1,2-dihydrocatechol 7, which is obtained by microbial oxidation of chlorobenzene, has been converted, via a sequence of reactions including ring-closing metathesis and Yamaguchi lactonisation steps, into the natural product (-)-cladospolide A (1).

    Original languageEnglish
    Pages (from-to)22-25
    Number of pages4
    JournalJournal of the Chemical Society, Perkin Transactions 1
    Volume2
    Issue number1
    Publication statusPublished - 2002

    Fingerprint

    Dive into the research topics of 'A chemoenzymatic synthesis of the 12-membered macrolide (-)-cladospolide A'. Together they form a unique fingerprint.

    Cite this