A chemoenzymatic synthesis of the 12-membered macrolide (-)-cladospolide A

M. G. Banwell; K. A. Jolliffe; D. T.J. Loong; K. J. McRae; F. Vounatsos

A chemoenzymatic synthesis of the 12-membered macrolide (-)-cladospolide A

M. G. Banwell^*, K. A. Jolliffe, D. T.J. Loong, K. J. McRae, F. Vounatsos

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

The enantiomerically pure cis-1,2-dihydrocatechol 7, which is obtained by microbial oxidation of chlorobenzene, has been converted, via a sequence of reactions including ring-closing metathesis and Yamaguchi lactonisation steps, into the natural product (-)-cladospolide A (1).

Original language	English
Pages (from-to)	22-25
Number of pages	4
Journal	Journal of the Chemical Society, Perkin Transactions 1
Volume	2
Issue number	1
Publication status	Published - 2002

Cite this

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title = "A chemoenzymatic synthesis of the 12-membered macrolide (-)-cladospolide A",

abstract = "The enantiomerically pure cis-1,2-dihydrocatechol 7, which is obtained by microbial oxidation of chlorobenzene, has been converted, via a sequence of reactions including ring-closing metathesis and Yamaguchi lactonisation steps, into the natural product (-)-cladospolide A (1).",

author = "Banwell, \{M. G.\} and Jolliffe, \{K. A.\} and Loong, \{D. T.J.\} and McRae, \{K. J.\} and F. Vounatsos",

year = "2002",

language = "English",

volume = "2",

pages = "22--25",

journal = "Journal of the Chemical Society, Perkin Transactions 1",

issn = "1472-7781",

publisher = "Chemical Society",

number = "1",

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T1 - A chemoenzymatic synthesis of the 12-membered macrolide (-)-cladospolide A

AU - Banwell, M. G.

AU - Jolliffe, K. A.

AU - Loong, D. T.J.

AU - McRae, K. J.

AU - Vounatsos, F.

PY - 2002

Y1 - 2002

N2 - The enantiomerically pure cis-1,2-dihydrocatechol 7, which is obtained by microbial oxidation of chlorobenzene, has been converted, via a sequence of reactions including ring-closing metathesis and Yamaguchi lactonisation steps, into the natural product (-)-cladospolide A (1).

AB - The enantiomerically pure cis-1,2-dihydrocatechol 7, which is obtained by microbial oxidation of chlorobenzene, has been converted, via a sequence of reactions including ring-closing metathesis and Yamaguchi lactonisation steps, into the natural product (-)-cladospolide A (1).

UR - https://www.scopus.com/pages/publications/0036006955

M3 - Article

SN - 1472-7781

VL - 2

SP - 22

EP - 25

JO - Journal of the Chemical Society, Perkin Transactions 1

JF - Journal of the Chemical Society, Perkin Transactions 1

IS - 1

ER -

A chemoenzymatic synthesis of the 12-membered macrolide (-)-cladospolide A

Abstract

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