A chemoenzymatic synthesis of the anti-influenza agent Tamiflu®

Maria Matveenko; Anthony C. Willis; Martin G. Banwell

doi:10.1016/j.tetlet.2008.09.130

A chemoenzymatic synthesis of the anti-influenza agent Tamiflu^®

Maria Matveenko, Anthony C. Willis, Martin G. Banwell^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

The anti-influenza drug Tamiflu^® is synthesized from enzymatically derived, enantiomerically pure, and readily available cis-1,2-dihydrocatechol.

Original language	English
Pages (from-to)	7018-7020
Number of pages	3
Journal	Tetrahedron Letters
Volume	49
Issue number	49
DOIs	https://doi.org/10.1016/j.tetlet.2008.09.130
Publication status	Published - 1 Dec 2008

Access to Document

10.1016/j.tetlet.2008.09.130

Cite this

@article{481302f31d4842448c95c1f192b4e899,

title = "A chemoenzymatic synthesis of the anti-influenza agent Tamiflu{\textregistered}",

abstract = "The anti-influenza drug Tamiflu{\textregistered} is synthesized from enzymatically derived, enantiomerically pure, and readily available cis-1,2-dihydrocatechol.",

keywords = "Acylaziridine, Anti-influenza, Synthesis, Tamiflu, cis-1,2-Dihydrocatechol",

author = "Maria Matveenko and Willis, \{Anthony C.\} and Banwell, \{Martin G.\}",

year = "2008",

month = dec,

day = "1",

doi = "10.1016/j.tetlet.2008.09.130",

language = "English",

volume = "49",

pages = "7018--7020",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd.",

number = "49",

}

TY - JOUR

T1 - A chemoenzymatic synthesis of the anti-influenza agent Tamiflu®

AU - Matveenko, Maria

AU - Willis, Anthony C.

AU - Banwell, Martin G.

PY - 2008/12/1

Y1 - 2008/12/1

N2 - The anti-influenza drug Tamiflu® is synthesized from enzymatically derived, enantiomerically pure, and readily available cis-1,2-dihydrocatechol.

AB - The anti-influenza drug Tamiflu® is synthesized from enzymatically derived, enantiomerically pure, and readily available cis-1,2-dihydrocatechol.

KW - Acylaziridine

KW - Anti-influenza

KW - Synthesis

KW - Tamiflu

KW - cis-1,2-Dihydrocatechol

UR - https://www.scopus.com/pages/publications/54049095827

U2 - 10.1016/j.tetlet.2008.09.130

DO - 10.1016/j.tetlet.2008.09.130

M3 - Article

SN - 0040-4039

VL - 49

SP - 7018

EP - 7020

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

A chemoenzymatic synthesis of the anti-influenza agent Tamiflu^®

Abstract

Access to Document

Other files and links

Fingerprint

Cite this