A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene

Martin G. Banwell; Mark J. Coster; Ochitha P. Karunaratne; Jason A. Smith

doi:10.1039/b205230j

A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene

Martin G. Banwell^*, Mark J. Coster, Ochitha P. Karunaratne, Jason A. Smith

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

The enantiomerically pure cis-1,2-diol 2, which is obtained by microbial oxidation of naphthalene, has been converted, via a sequence of reactions including oxidative C – C bond cleavage, decarbonylation and ring-closing metathesis steps, into the natural product (+)-goniodiol (1).

Original language	English
Pages (from-to)	1622-1624
Number of pages	3
Journal	Journal of the Chemical Society, Perkin Transactions 1
Volume	2
Issue number	14
DOIs	https://doi.org/10.1039/b205230j
Publication status	Published - 29 May 2002

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title = "A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene",

abstract = "The enantiomerically pure cis-1,2-diol 2, which is obtained by microbial oxidation of naphthalene, has been converted, via a sequence of reactions including oxidative C – C bond cleavage, decarbonylation and ring-closing metathesis steps, into the natural product (+)-goniodiol (1).",

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AU - Smith, Jason A.

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AB - The enantiomerically pure cis-1,2-diol 2, which is obtained by microbial oxidation of naphthalene, has been converted, via a sequence of reactions including oxidative C – C bond cleavage, decarbonylation and ring-closing metathesis steps, into the natural product (+)-goniodiol (1).

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A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene

Abstract

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