A chemoenzymatic total synthesis of the structure assigned to the alkaloid (+)-montabuphine

Maria Matveenko; Martin G. Banwell; Anthony C. Willis

doi:10.1021/ol801815k

A chemoenzymatic total synthesis of the structure assigned to the alkaloid (+)-montabuphine

Maria Matveenko^*, Martin G. Banwell, Anthony C. Willis

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

(Chemical Equation Presented) An enantioselective synthesis of the structure, 3, assigned to the alkaloid (+)-montabuphine has been achieved using the readily available metabolite 4 as starting material. A comparison of the physical and spectral data recorded on compound 3 with those reported for (+)-montabuphine suggests that they are different compounds.

Original language	English
Pages (from-to)	4693-4696
Number of pages	4
Journal	Organic Letters
Volume	10
Issue number	20
DOIs	https://doi.org/10.1021/ol801815k
Publication status	Published - 2008

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10.1021/ol801815k

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title = "A chemoenzymatic total synthesis of the structure assigned to the alkaloid (+)-montabuphine",

abstract = "(Chemical Equation Presented) An enantioselective synthesis of the structure, 3, assigned to the alkaloid (+)-montabuphine has been achieved using the readily available metabolite 4 as starting material. A comparison of the physical and spectral data recorded on compound 3 with those reported for (+)-montabuphine suggests that they are different compounds.",

author = "Maria Matveenko and Banwell, {Martin G.} and Willis, {Anthony C.}",

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T1 - A chemoenzymatic total synthesis of the structure assigned to the alkaloid (+)-montabuphine

AU - Matveenko, Maria

AU - Banwell, Martin G.

AU - Willis, Anthony C.

PY - 2008

Y1 - 2008

N2 - (Chemical Equation Presented) An enantioselective synthesis of the structure, 3, assigned to the alkaloid (+)-montabuphine has been achieved using the readily available metabolite 4 as starting material. A comparison of the physical and spectral data recorded on compound 3 with those reported for (+)-montabuphine suggests that they are different compounds.

AB - (Chemical Equation Presented) An enantioselective synthesis of the structure, 3, assigned to the alkaloid (+)-montabuphine has been achieved using the readily available metabolite 4 as starting material. A comparison of the physical and spectral data recorded on compound 3 with those reported for (+)-montabuphine suggests that they are different compounds.

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U2 - 10.1021/ol801815k

DO - 10.1021/ol801815k

M3 - Article

SN - 1523-7060

VL - 10

SP - 4693

EP - 4696

JO - Organic Letters

JF - Organic Letters

IS - 20

ER -

A chemoenzymatic total synthesis of the structure assigned to the alkaloid (+)-montabuphine

Abstract

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