A formal total synthesis of platencin

Kerrie A.B. Austin; Martin G. Banwell; Anthony C. Willis

doi:10.1021/ol801647h

A formal total synthesis of platencin

Kerrie A.B. Austin^*, Martin G. Banwell, Anthony C. Willis

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

59 Citations (Scopus)

Abstract

(Chemical Equation Presented) The readily available and enantiomerically pure trienes 12 undergo a thermally induced intramolecular Diels-Alder reaction to give the corresponding mixture of compounds 13 and 14. This mixture has been elaborated to an advanced intermediate associated with Nicolaou's recently reported total synthesis of the natural enantiomeric form of the antibiotic platencin (2).

Original language	English
Pages (from-to)	4465-4468
Number of pages	4
Journal	Organic Letters
Volume	10
Issue number	20
DOIs	https://doi.org/10.1021/ol801647h
Publication status	Published - 2008

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10.1021/ol801647h

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title = "A formal total synthesis of platencin",

abstract = "(Chemical Equation Presented) The readily available and enantiomerically pure trienes 12 undergo a thermally induced intramolecular Diels-Alder reaction to give the corresponding mixture of compounds 13 and 14. This mixture has been elaborated to an advanced intermediate associated with Nicolaou's recently reported total synthesis of the natural enantiomeric form of the antibiotic platencin (2).",

author = "Austin, {Kerrie A.B.} and Banwell, {Martin G.} and Willis, {Anthony C.}",

year = "2008",

doi = "10.1021/ol801647h",

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T1 - A formal total synthesis of platencin

AU - Austin, Kerrie A.B.

AU - Banwell, Martin G.

AU - Willis, Anthony C.

PY - 2008

Y1 - 2008

N2 - (Chemical Equation Presented) The readily available and enantiomerically pure trienes 12 undergo a thermally induced intramolecular Diels-Alder reaction to give the corresponding mixture of compounds 13 and 14. This mixture has been elaborated to an advanced intermediate associated with Nicolaou's recently reported total synthesis of the natural enantiomeric form of the antibiotic platencin (2).

AB - (Chemical Equation Presented) The readily available and enantiomerically pure trienes 12 undergo a thermally induced intramolecular Diels-Alder reaction to give the corresponding mixture of compounds 13 and 14. This mixture has been elaborated to an advanced intermediate associated with Nicolaou's recently reported total synthesis of the natural enantiomeric form of the antibiotic platencin (2).

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U2 - 10.1021/ol801647h

DO - 10.1021/ol801647h

M3 - Article

SN - 1523-7060

VL - 10

SP - 4465

EP - 4468

JO - Organic Letters

JF - Organic Letters

IS - 20

ER -

A formal total synthesis of platencin

Abstract

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