A metalation strategy for the construction of functionalized naphthalenes: The first synthesis of guieranone A

Malcolm W.B. McCulloch; Russell A. Barrow

doi:10.1016/j.tetlet.2005.08.127

A metalation strategy for the construction of functionalized naphthalenes: The first synthesis of guieranone A

Malcolm W.B. McCulloch, Russell A. Barrow^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

The first synthesis of the natural product guieranone A is described, demonstrating a one-pot procedure for the synthesis of protected-1,3,6,8- tetraoxygenated naphthalenes and a subsequent directed metalation synthesis of 2-keto naphthalenes.

Original language	English
Pages (from-to)	7619-7621
Number of pages	3
Journal	Tetrahedron Letters
Volume	46
Issue number	44
DOIs	https://doi.org/10.1016/j.tetlet.2005.08.127
Publication status	Published - 31 Oct 2005

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10.1016/j.tetlet.2005.08.127

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title = "A metalation strategy for the construction of functionalized naphthalenes: The first synthesis of guieranone A",

abstract = "The first synthesis of the natural product guieranone A is described, demonstrating a one-pot procedure for the synthesis of protected-1,3,6,8- tetraoxygenated naphthalenes and a subsequent directed metalation synthesis of 2-keto naphthalenes.",

keywords = "Dieckmann cyclization, Guieranone, Metalation, Naphthalenes, Natural product",

author = "McCulloch, {Malcolm W.B.} and Barrow, {Russell A.}",

year = "2005",

month = oct,

day = "31",

doi = "10.1016/j.tetlet.2005.08.127",

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journal = "Tetrahedron Letters",

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T2 - The first synthesis of guieranone A

AU - McCulloch, Malcolm W.B.

AU - Barrow, Russell A.

PY - 2005/10/31

Y1 - 2005/10/31

N2 - The first synthesis of the natural product guieranone A is described, demonstrating a one-pot procedure for the synthesis of protected-1,3,6,8- tetraoxygenated naphthalenes and a subsequent directed metalation synthesis of 2-keto naphthalenes.

AB - The first synthesis of the natural product guieranone A is described, demonstrating a one-pot procedure for the synthesis of protected-1,3,6,8- tetraoxygenated naphthalenes and a subsequent directed metalation synthesis of 2-keto naphthalenes.

KW - Dieckmann cyclization

KW - Guieranone

KW - Metalation

KW - Naphthalenes

KW - Natural product

UR - http://www.scopus.com/inward/record.url?scp=26244468386&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2005.08.127

DO - 10.1016/j.tetlet.2005.08.127

M3 - Article

SN - 0040-4039

VL - 46

SP - 7619

EP - 7621

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 44

ER -

A metalation strategy for the construction of functionalized naphthalenes: The first synthesis of guieranone A

Abstract

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