A Paleogenomic Reconstruction of the Deep Population History of the Andes

Nathan Nakatsuka; Iosif Lazaridis; Chiara Barbieri; Pontus Skoglund; Nadin Rohland; Swapan Mallick; Cosimo Posth; Kelly Harkins-Kinkaid; Matthew Ferry; Éadaoin Harney; Megan Michel; Kristin Stewardson; Jannine Novak-Forst; José M. Capriles; Marta Alfonso Durruty; Karina Aranda Álvarez; David Beresford-Jones; Richard Burger; Lauren Cadwallader; Ricardo Fujita; Johny Isla; George Lau; Carlos Lémuz Aguirre; Steven LeBlanc; Sergio Calla Maldonado; Frank Meddens; Pablo G. Messineo; Brendan J. Culleton; Thomas K. Harper; Jeffrey Quilter; Gustavo Politis; Kurt Rademaker; Markus Reindel; Mario Rivera; Lucy Salazar; José R. Sandoval; Calogero M. Santoro; Nahuel Scheifler; Vivien Standen; Maria Ines Barreto; Isabel Flores Espinoza; Elsa Tomasto-Cagigao; Guido Valverde; Douglas J. Kennett; Alan Cooper; Johannes Krause; Wolfgang Haak; Bastien Llamas; David Reich; Lars Fehren-Schmitz

doi:10.1016/j.cell.2020.04.015

A Paleogenomic Reconstruction of the Deep Population History of the Andes

Nathan Nakatsuka^*, Iosif Lazaridis, Chiara Barbieri, Pontus Skoglund, Nadin Rohland, Swapan Mallick, Cosimo Posth, Kelly Harkins-Kinkaid, Matthew Ferry, Éadaoin Harney, Megan Michel, Kristin Stewardson, Jannine Novak-Forst, José M. Capriles, Marta Alfonso Durruty, Karina Aranda Álvarez, David Beresford-Jones, Richard Burger, Lauren Cadwallader, Ricardo FujitaJohny Isla, George Lau, Carlos Lémuz Aguirre, Steven LeBlanc, Sergio Calla Maldonado, Frank Meddens, Pablo G. Messineo, Brendan J. Culleton, Thomas K. Harper, Jeffrey Quilter, Gustavo Politis, Kurt Rademaker, Markus Reindel, Mario Rivera, Lucy Salazar, José R. Sandoval, Calogero M. Santoro, Nahuel Scheifler, Vivien Standen, Maria Ines Barreto, Isabel Flores Espinoza, Elsa Tomasto-Cagigao, Guido Valverde, Douglas J. Kennett, Alan Cooper, Johannes Krause, Wolfgang Haak, Bastien Llamas, David Reich^*, Lars Fehren-Schmitz^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

Abstract

There are many unanswered questions about the population history of the Central and South Central Andes, particularly regarding the impact of large-scale societies, such as the Moche, Wari, Tiwanaku, and Inca. We assembled genome-wide data on 89 individuals dating from ∼9,000-500 years ago (BP), with a particular focus on the period of the rise and fall of state societies. Today's genetic structure began to develop by 5,800 BP, followed by bi-directional gene flow between the North and South Highlands, and between the Highlands and Coast. We detect minimal admixture among neighboring groups between ∼2,000–500 BP, although we do detect cosmopolitanism (people of diverse ancestries living side-by-side) in the heartlands of the Tiwanaku and Inca polities. We also highlight cases of long-range mobility connecting the Andes to Argentina and the Northwest Andes to the Amazon Basin. Video Abstract: [Figure presented] Genome-wide data from 89 ancient humans illuminates the changes to the genetic landscape in the Central Andes over 9,000 years, revealing large-scale gene flow and cosmopolitan societies in the Tiwanaku and Inca polities.

Original language	English
Pages (from-to)	1131-1145.e21
Journal	Cell
Volume	181
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2020.04.015
Publication status	Published - 28 May 2020
Externally published	Yes

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Nakatsuka, N., Lazaridis, I., Barbieri, C., Skoglund, P., Rohland, N., Mallick, S., Posth, C., Harkins-Kinkaid, K., Ferry, M., Harney, É., Michel, M., Stewardson, K., Novak-Forst, J., Capriles, J. M., Durruty, M. A., Álvarez, K. A., Beresford-Jones, D., Burger, R., Cadwallader, L., ... Fehren-Schmitz, L. (2020). A Paleogenomic Reconstruction of the Deep Population History of the Andes. Cell, 181(5), 1131-1145.e21. https://doi.org/10.1016/j.cell.2020.04.015

@article{a2cc0fe2263340beadba777af0393dfa,

title = "A Paleogenomic Reconstruction of the Deep Population History of the Andes",

abstract = "There are many unanswered questions about the population history of the Central and South Central Andes, particularly regarding the impact of large-scale societies, such as the Moche, Wari, Tiwanaku, and Inca. We assembled genome-wide data on 89 individuals dating from ∼9,000-500 years ago (BP), with a particular focus on the period of the rise and fall of state societies. Today's genetic structure began to develop by 5,800 BP, followed by bi-directional gene flow between the North and South Highlands, and between the Highlands and Coast. We detect minimal admixture among neighboring groups between ∼2,000–500 BP, although we do detect cosmopolitanism (people of diverse ancestries living side-by-side) in the heartlands of the Tiwanaku and Inca polities. We also highlight cases of long-range mobility connecting the Andes to Argentina and the Northwest Andes to the Amazon Basin. Video Abstract: [Figure presented] Genome-wide data from 89 ancient humans illuminates the changes to the genetic landscape in the Central Andes over 9,000 years, revealing large-scale gene flow and cosmopolitan societies in the Tiwanaku and Inca polities.",

keywords = "ancient DNA, Andes, anthropology, archaeology, population genetics",

author = "Nathan Nakatsuka and Iosif Lazaridis and Chiara Barbieri and Pontus Skoglund and Nadin Rohland and Swapan Mallick and Cosimo Posth and Kelly Harkins-Kinkaid and Matthew Ferry and {\'E}adaoin Harney and Megan Michel and Kristin Stewardson and Jannine Novak-Forst and Capriles, {Jos{\'e} M.} and Durruty, {Marta Alfonso} and {\'A}lvarez, {Karina Aranda} and David Beresford-Jones and Richard Burger and Lauren Cadwallader and Ricardo Fujita and Johny Isla and George Lau and Aguirre, {Carlos L{\'e}muz} and Steven LeBlanc and Maldonado, {Sergio Calla} and Frank Meddens and Messineo, {Pablo G.} and Culleton, {Brendan J.} and Harper, {Thomas K.} and Jeffrey Quilter and Gustavo Politis and Kurt Rademaker and Markus Reindel and Mario Rivera and Lucy Salazar and Sandoval, {Jos{\'e} R.} and Santoro, {Calogero M.} and Nahuel Scheifler and Vivien Standen and Barreto, {Maria Ines} and Espinoza, {Isabel Flores} and Elsa Tomasto-Cagigao and Guido Valverde and Kennett, {Douglas J.} and Alan Cooper and Johannes Krause and Wolfgang Haak and Bastien Llamas and David Reich and Lars Fehren-Schmitz",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = may,

day = "28",

doi = "10.1016/j.cell.2020.04.015",

language = "English",

volume = "181",

pages = "1131--1145.e21",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier B.V.",

number = "5",

}

Nakatsuka, N, Lazaridis, I, Barbieri, C, Skoglund, P, Rohland, N, Mallick, S, Posth, C, Harkins-Kinkaid, K, Ferry, M, Harney, É, Michel, M, Stewardson, K, Novak-Forst, J, Capriles, JM, Durruty, MA, Álvarez, KA, Beresford-Jones, D, Burger, R, Cadwallader, L, Fujita, R, Isla, J, Lau, G, Aguirre, CL, LeBlanc, S, Maldonado, SC, Meddens, F, Messineo, PG, Culleton, BJ, Harper, TK, Quilter, J, Politis, G, Rademaker, K, Reindel, M, Rivera, M, Salazar, L, Sandoval, JR, Santoro, CM, Scheifler, N, Standen, V, Barreto, MI, Espinoza, IF, Tomasto-Cagigao, E, Valverde, G, Kennett, DJ, Cooper, A, Krause, J, Haak, W, Llamas, B, Reich, D & Fehren-Schmitz, L 2020, 'A Paleogenomic Reconstruction of the Deep Population History of the Andes', Cell, vol. 181, no. 5, pp. 1131-1145.e21. https://doi.org/10.1016/j.cell.2020.04.015

TY - JOUR

T1 - A Paleogenomic Reconstruction of the Deep Population History of the Andes

AU - Nakatsuka, Nathan

AU - Lazaridis, Iosif

AU - Barbieri, Chiara

AU - Skoglund, Pontus

AU - Rohland, Nadin

AU - Mallick, Swapan

AU - Posth, Cosimo

AU - Harkins-Kinkaid, Kelly

AU - Ferry, Matthew

AU - Harney, Éadaoin

AU - Michel, Megan

AU - Stewardson, Kristin

AU - Novak-Forst, Jannine

AU - Capriles, José M.

AU - Durruty, Marta Alfonso

AU - Álvarez, Karina Aranda

AU - Beresford-Jones, David

AU - Burger, Richard

AU - Cadwallader, Lauren

AU - Fujita, Ricardo

AU - Isla, Johny

AU - Lau, George

AU - Aguirre, Carlos Lémuz

AU - LeBlanc, Steven

AU - Maldonado, Sergio Calla

AU - Meddens, Frank

AU - Messineo, Pablo G.

AU - Culleton, Brendan J.

AU - Harper, Thomas K.

AU - Quilter, Jeffrey

AU - Politis, Gustavo

AU - Rademaker, Kurt

AU - Reindel, Markus

AU - Rivera, Mario

AU - Salazar, Lucy

AU - Sandoval, José R.

AU - Santoro, Calogero M.

AU - Scheifler, Nahuel

AU - Standen, Vivien

AU - Barreto, Maria Ines

AU - Espinoza, Isabel Flores

AU - Tomasto-Cagigao, Elsa

AU - Valverde, Guido

AU - Kennett, Douglas J.

AU - Cooper, Alan

AU - Krause, Johannes

AU - Haak, Wolfgang

AU - Llamas, Bastien

AU - Reich, David

AU - Fehren-Schmitz, Lars

PY - 2020/5/28

Y1 - 2020/5/28

N2 - There are many unanswered questions about the population history of the Central and South Central Andes, particularly regarding the impact of large-scale societies, such as the Moche, Wari, Tiwanaku, and Inca. We assembled genome-wide data on 89 individuals dating from ∼9,000-500 years ago (BP), with a particular focus on the period of the rise and fall of state societies. Today's genetic structure began to develop by 5,800 BP, followed by bi-directional gene flow between the North and South Highlands, and between the Highlands and Coast. We detect minimal admixture among neighboring groups between ∼2,000–500 BP, although we do detect cosmopolitanism (people of diverse ancestries living side-by-side) in the heartlands of the Tiwanaku and Inca polities. We also highlight cases of long-range mobility connecting the Andes to Argentina and the Northwest Andes to the Amazon Basin. Video Abstract: [Figure presented] Genome-wide data from 89 ancient humans illuminates the changes to the genetic landscape in the Central Andes over 9,000 years, revealing large-scale gene flow and cosmopolitan societies in the Tiwanaku and Inca polities.

AB - There are many unanswered questions about the population history of the Central and South Central Andes, particularly regarding the impact of large-scale societies, such as the Moche, Wari, Tiwanaku, and Inca. We assembled genome-wide data on 89 individuals dating from ∼9,000-500 years ago (BP), with a particular focus on the period of the rise and fall of state societies. Today's genetic structure began to develop by 5,800 BP, followed by bi-directional gene flow between the North and South Highlands, and between the Highlands and Coast. We detect minimal admixture among neighboring groups between ∼2,000–500 BP, although we do detect cosmopolitanism (people of diverse ancestries living side-by-side) in the heartlands of the Tiwanaku and Inca polities. We also highlight cases of long-range mobility connecting the Andes to Argentina and the Northwest Andes to the Amazon Basin. Video Abstract: [Figure presented] Genome-wide data from 89 ancient humans illuminates the changes to the genetic landscape in the Central Andes over 9,000 years, revealing large-scale gene flow and cosmopolitan societies in the Tiwanaku and Inca polities.

KW - ancient DNA

KW - Andes

KW - anthropology

KW - archaeology

KW - population genetics

UR - http://www.scopus.com/inward/record.url?scp=85085031443&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2020.04.015

DO - 10.1016/j.cell.2020.04.015

M3 - Article

C2 - 32386546

AN - SCOPUS:85085031443

SN - 0092-8674

VL - 181

SP - 1131-1145.e21

JO - Cell

JF - Cell

IS - 5

ER -

A Paleogenomic Reconstruction of the Deep Population History of the Andes

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