TY - JOUR
T1 - A paradigm shift in the origin of ovarian cancer
T2 - the ovary is no longer to blame
AU - Meyn, Ashleigh
AU - Lim, Boon
PY - 2017/5
Y1 - 2017/5
N2 - Ovarian cancer is the most aggressive and lethal gynaecological cancer. High-grade serous carcinoma (HGSC) is the most common subtype, comprising 75% of ovarian cancers, and has the lowest survival rate. Most women with HGSC present with advanced disease (stage III or IV) at which time the 5-year survival is between 20% and 40%. There is currently no effective screening regimen for ovarian cancer and long-term cure rates have not changed dramatically in over 20 years.
AB - Ovarian cancer is the most aggressive and lethal gynaecological cancer. High-grade serous carcinoma (HGSC) is the most common subtype, comprising 75% of ovarian cancers, and has the lowest survival rate. Most women with HGSC present with advanced disease (stage III or IV) at which time the 5-year survival is between 20% and 40%. There is currently no effective screening regimen for ovarian cancer and long-term cure rates have not changed dramatically in over 20 years.
UR - http://www.scopus.com/inward/record.url?scp=85018734272&partnerID=8YFLogxK
U2 - 10.1111/1471-0528.14609
DO - 10.1111/1471-0528.14609
M3 - Comment/debate
SN - 1470-0328
VL - 124
SP - 859
JO - BJOG: An International Journal of Obstetrics and Gynaecology
JF - BJOG: An International Journal of Obstetrics and Gynaecology
IS - 6
ER -