A paradigm shift in the origin of ovarian cancer: the ovary is no longer to blame

Ashleigh Meyn; Boon Lim

doi:10.1111/1471-0528.14609

A paradigm shift in the origin of ovarian cancer: the ovary is no longer to blame

Ashleigh Meyn
, Boon Lim

Research output: Contribution to journal › Comment/debate › peer-review

5 Citations (Scopus)

Abstract

Ovarian cancer is the most aggressive and lethal gynaecological cancer. High-grade serous carcinoma (HGSC) is the most common subtype, comprising 75% of ovarian cancers, and has the lowest survival rate. Most women with HGSC present with advanced disease (stage III or IV) at which time the 5-year survival is between 20% and 40%. There is currently no effective screening regimen for ovarian cancer and long-term cure rates have not changed dramatically in over 20 years.

Original language	English
Pages (from-to)	859
Number of pages	1
Journal	BJOG: An International Journal of Obstetrics and Gynaecology
Volume	124
Issue number	6
DOIs	https://doi.org/10.1111/1471-0528.14609
Publication status	Published - May 2017
Externally published	Yes

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10.1111/1471-0528.14609

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title = "A paradigm shift in the origin of ovarian cancer: the ovary is no longer to blame",

abstract = "Ovarian cancer is the most aggressive and lethal gynaecological cancer. High-grade serous carcinoma (HGSC) is the most common subtype, comprising 75\% of ovarian cancers, and has the lowest survival rate. Most women with HGSC present with advanced disease (stage III or IV) at which time the 5-year survival is between 20\% and 40\%. There is currently no effective screening regimen for ovarian cancer and long-term cure rates have not changed dramatically in over 20 years.",

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AU - Lim, Boon

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N2 - Ovarian cancer is the most aggressive and lethal gynaecological cancer. High-grade serous carcinoma (HGSC) is the most common subtype, comprising 75% of ovarian cancers, and has the lowest survival rate. Most women with HGSC present with advanced disease (stage III or IV) at which time the 5-year survival is between 20% and 40%. There is currently no effective screening regimen for ovarian cancer and long-term cure rates have not changed dramatically in over 20 years.

AB - Ovarian cancer is the most aggressive and lethal gynaecological cancer. High-grade serous carcinoma (HGSC) is the most common subtype, comprising 75% of ovarian cancers, and has the lowest survival rate. Most women with HGSC present with advanced disease (stage III or IV) at which time the 5-year survival is between 20% and 40%. There is currently no effective screening regimen for ovarian cancer and long-term cure rates have not changed dramatically in over 20 years.

UR - https://www.scopus.com/pages/publications/85018734272

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DO - 10.1111/1471-0528.14609

M3 - Comment/debate

SN - 1470-0328

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SP - 859

JO - BJOG: An International Journal of Obstetrics and Gynaecology

JF - BJOG: An International Journal of Obstetrics and Gynaecology

IS - 6

ER -

A paradigm shift in the origin of ovarian cancer: the ovary is no longer to blame

Abstract

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