A Real World Study on Adjuvant Nivolumab: Recurrence Free Survival and Toxicity in Resected Stage III and IV Melanoma [Meeting Abstract]

Wendy E. Huang, Christine Archer, Desmond Yip, Yada Kanjanapan, Geoffrey Peters

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    Abstract

    Background: Nivolumab, a human IgG4 monoclonal antibody against programmed death 1 (PD-1), is approved for metastatic melanoma. The CheckMate 238 trial demonstrated one year of adjuvant nivolumab, compared with ipilimumab in resected Stage III and IV melanoma, provided longer recurrence-free survival (RFS) and lower incidence of immune related adverse events (irAEs). Patients with resected stage III and IV melanoma received adjuvant nivolumab via a patient access program (PAP) from August 2018 at our institution. This study examined local data regarding RFS and irAEs in this cohort.

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