ABC ! ABCE/D based approaches to the pentacyclic ring system of the vinca alkaloids using intramolecular hetero-[2+2]cycloaddition and gold(i)-catalysed 6-endo-dig cyclisation protocols

Chemistry

• Cyclic Structure 100%
• Vinca Alkaloid 100%
• Occurrence in Nature 50%
• Chemistry 50%
• Indole 50%
• Azide 50%
• Imine 50%
• Cyclization Reaction 50%
• Photolysis 50%
• Enamide 50%
• Fischer Synthesis 50%
• Ketal 50%
• Isothiocyanate 50%
• cyclohexane-1,4-dione 50%