Aberrant CD8⁺ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling

Immunology and Microbiology

• Mouse Model 100%
• Viral Disease 100%
• Cytotoxic T-Cell 100%
• Mammalian Target of Rapamycin Complex 1 100%
• Ataxia Telangiectasia 100%
• Memory T Cell 60%
• T Cell Receptor 60%
• Immune System 40%
• Mouse Mutant 40%
• T Cell Development 40%
• Lymphocytic Choriomeningitis Virus 40%
• Interleukin 15 40%
• Immune Response 20%
• Mouse 20%
• Cytokine 20%
• Epitope 20%
• Immunodominance 20%
• Cytokine Response 20%
• Sirolimus 20%

Biochemistry, Genetics and Molecular Biology

• Mouse Model 100%
• T Cell 100%
• Mammalian Target of Rapamycin Complex 1 100%
• CD8 100%
• T Cell Receptor 60%
• Memory T Cell 60%
• Cell Maturation 40%
• Mouse Mutant 40%
• Lymphocytic Choriomeningitis Virus 40%
• Interleukin 15 40%
• Immune Response 20%
• Mouse 20%
• Protein Kinases 20%
• Cytokine 20%
• Ribosomal Protein S6 20%
• Cytokine Response 20%

Neuroscience

• T Cell 100%
• CD8 100%
• Ataxia Telangiectasia 100%
• Mammalian Target of Rapamycin Complex 1 100%
• T Lymphocyte Receptor 37%
• Cell Maturation 25%
• Interleukin 15 25%
• Lymphocytic Choriomeningitis Virus 25%
• In Vivo 12%
• Epitope 12%
• Protein Kinases 12%
• Protein S6 12%
• Protein Kinase B 12%