TY - JOUR
T1 - Adrenaline-induced hypotension in neurosurgery
AU - Phillips, S.
AU - Hutchinson, S. E.
AU - Bayly, P.
AU - Hollway, T. E.
PY - 1993/6
Y1 - 1993/6
N2 - Summary: We have compared the effects of scalp infiltration with 0.5% lignocaine, 0.5% lignocaine with adrenaline 1:200000, 0.9% saline and 0.9% saline with adrenaline 1:200000, in a prospective, randomized, double-blind study. Direct arterial pressure, heart rate and bleeding at incision were recorded in 80 patients undergoing craniotomy or craniectomy. Arterial pressure decreased by more than 20% from preinfiltration values in 40% of patients in the saline with adrenaline group, and in 55% of patients in the lignocaine with adrenaline group. It did not decrease in patients who did not receive adrenaline. (Br. J. Anaesth. 1993; 70: 687-688).
AB - Summary: We have compared the effects of scalp infiltration with 0.5% lignocaine, 0.5% lignocaine with adrenaline 1:200000, 0.9% saline and 0.9% saline with adrenaline 1:200000, in a prospective, randomized, double-blind study. Direct arterial pressure, heart rate and bleeding at incision were recorded in 80 patients undergoing craniotomy or craniectomy. Arterial pressure decreased by more than 20% from preinfiltration values in 40% of patients in the saline with adrenaline group, and in 55% of patients in the lignocaine with adrenaline group. It did not decrease in patients who did not receive adrenaline. (Br. J. Anaesth. 1993; 70: 687-688).
KW - Anaesthesia: neurosurgical
KW - Complications cariovascular responses
KW - Sympathetic nervous system: beta-adrenergic agonists, subcutaneous adrenaline
UR - http://www.scopus.com/inward/record.url?scp=0027158379&partnerID=8YFLogxK
U2 - 10.1093/bja/70.6.687
DO - 10.1093/bja/70.6.687
M3 - Article
SN - 0007-0912
VL - 70
SP - 687
EP - 688
JO - British Journal of Anaesthesia
JF - British Journal of Anaesthesia
IS - 6
ER -