Alkaloids from marine organisms. Part 8: Isolation of bisdemethylaaptamine and bisdemethylaaptamine-9-O-sulfate from an Indonesian Aaptos sp. marine sponge

Anthony Herlt; Lewis Mander; Wilson Rombang; Rymond Rumampuk; Soetijoso Soemitro; Wolfgang Steglich; Ponis Tarigan; Franz Von Nussbaum

doi:10.1016/j.tet.2004.05.068

Alkaloids from marine organisms. Part 8: Isolation of bisdemethylaaptamine and bisdemethylaaptamine-9-O-sulfate from an Indonesian Aaptos sp. marine sponge

Anthony Herlt^*, Lewis Mander, Wilson Rombang, Rymond Rumampuk, Soetijoso Soemitro, Wolfgang Steglich, Ponis Tarigan, Franz Von Nussbaum

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Bisdemethylaaptamine (6), a proposed biosynthetic precursor of the aaptamines has been isolated from an Aaptos sp. marine sponge harvested off the Indonesian coast, and its identity confirmed by comparison of its spectral data with that of synthetic material. Bisdemethylaaptamine-9-O-sulfate (7) was also isolated from the same source. This is the first report of a sulfated aaptamine.

Original language	English
Pages (from-to)	6101-6104
Number of pages	4
Journal	Tetrahedron
Volume	60
Issue number	29
DOIs	https://doi.org/10.1016/j.tet.2004.05.068
Publication status	Published - 12 Jul 2004

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10.1016/j.tet.2004.05.068

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title = "Alkaloids from marine organisms. Part 8: Isolation of bisdemethylaaptamine and bisdemethylaaptamine-9-O-sulfate from an Indonesian Aaptos sp. marine sponge",

abstract = "Bisdemethylaaptamine (6), a proposed biosynthetic precursor of the aaptamines has been isolated from an Aaptos sp. marine sponge harvested off the Indonesian coast, and its identity confirmed by comparison of its spectral data with that of synthetic material. Bisdemethylaaptamine-9-O-sulfate (7) was also isolated from the same source. This is the first report of a sulfated aaptamine.",

keywords = "Aaptos, Bisdemethylaaptamine, Sulfated aaptamines",

author = "Anthony Herlt and Lewis Mander and Wilson Rombang and Rymond Rumampuk and Soetijoso Soemitro and Wolfgang Steglich and Ponis Tarigan and {Von Nussbaum}, Franz",

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T2 - Isolation of bisdemethylaaptamine and bisdemethylaaptamine-9-O-sulfate from an Indonesian Aaptos sp. marine sponge

AU - Herlt, Anthony

AU - Mander, Lewis

AU - Rombang, Wilson

AU - Rumampuk, Rymond

AU - Soemitro, Soetijoso

AU - Steglich, Wolfgang

AU - Tarigan, Ponis

AU - Von Nussbaum, Franz

PY - 2004/7/12

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N2 - Bisdemethylaaptamine (6), a proposed biosynthetic precursor of the aaptamines has been isolated from an Aaptos sp. marine sponge harvested off the Indonesian coast, and its identity confirmed by comparison of its spectral data with that of synthetic material. Bisdemethylaaptamine-9-O-sulfate (7) was also isolated from the same source. This is the first report of a sulfated aaptamine.

AB - Bisdemethylaaptamine (6), a proposed biosynthetic precursor of the aaptamines has been isolated from an Aaptos sp. marine sponge harvested off the Indonesian coast, and its identity confirmed by comparison of its spectral data with that of synthetic material. Bisdemethylaaptamine-9-O-sulfate (7) was also isolated from the same source. This is the first report of a sulfated aaptamine.

KW - Aaptos

KW - Bisdemethylaaptamine

KW - Sulfated aaptamines

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IS - 29

ER -

Alkaloids from marine organisms. Part 8: Isolation of bisdemethylaaptamine and bisdemethylaaptamine-9-O-sulfate from an Indonesian Aaptos sp. marine sponge

Abstract

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