ALPK1: innate attraction to the sweetness of bacteria

Yansong Xue; Si Ming Man

doi:10.1038/s41422-018-0100-0

ALPK1: innate attraction to the sweetness of bacteria

Yansong Xue, Si Ming Man^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate › peer-review

4 Citations (Scopus)

Abstract

Pattern-recognition receptors (PRRs) have critical roles in mediating the recognition of microbial and danger signals. A recent study by Zhou et al. published in Nature demonstrates that ALPK1 is a cytosolic PRR, which recognizes the bacterial metabolite ADP-Hep, triggering activation of the inflammatory NF-ÎºB signaling pathway.

Original language	English
Pages (from-to)	1125-1126
Number of pages	2
Journal	Cell Research
Volume	28
Issue number	12
DOIs	https://doi.org/10.1038/s41422-018-0100-0
Publication status	Published - 1 Dec 2018

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title = "ALPK1: innate attraction to the sweetness of bacteria",

abstract = "Pattern-recognition receptors (PRRs) have critical roles in mediating the recognition of microbial and danger signals. A recent study by Zhou et al. published in Nature demonstrates that ALPK1 is a cytosolic PRR, which recognizes the bacterial metabolite ADP-Hep, triggering activation of the inflammatory NF-{\^I}ºB signaling pathway.",

author = "Yansong Xue and Man, {Si Ming}",

year = "2018",

month = dec,

day = "1",

doi = "10.1038/s41422-018-0100-0",

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journal = "Cell Research",

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T1 - ALPK1

T2 - innate attraction to the sweetness of bacteria

AU - Xue, Yansong

AU - Man, Si Ming

PY - 2018/12/1

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N2 - Pattern-recognition receptors (PRRs) have critical roles in mediating the recognition of microbial and danger signals. A recent study by Zhou et al. published in Nature demonstrates that ALPK1 is a cytosolic PRR, which recognizes the bacterial metabolite ADP-Hep, triggering activation of the inflammatory NF-ÎºB signaling pathway.

AB - Pattern-recognition receptors (PRRs) have critical roles in mediating the recognition of microbial and danger signals. A recent study by Zhou et al. published in Nature demonstrates that ALPK1 is a cytosolic PRR, which recognizes the bacterial metabolite ADP-Hep, triggering activation of the inflammatory NF-ÎºB signaling pathway.

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U2 - 10.1038/s41422-018-0100-0

DO - 10.1038/s41422-018-0100-0

M3 - Comment/debate

SN - 1001-0602

VL - 28

SP - 1125

EP - 1126

JO - Cell Research

JF - Cell Research

IS - 12

ER -

ALPK1: innate attraction to the sweetness of bacteria

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