An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms

A. F. Jorm; A. S. Henderson; P. A. Jacomb; H. Christensen; A. E. Körten; B. Rodgers; X. Tan; S. Easteal

doi:10.1038/sj.mp.4000424

An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms

A. F. Jorm^*, A. S. Henderson, P. A. Jacomb, H. Christensen, A. E. Körten, B. Rodgers, X. Tan, S. Easteal

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

123 Citations (Scopus)

Abstract

A functional polymorphism in the regulatory region of the serotonin transporter gene has been reported to be associated with anxiety-related personality traits. We attempted to replicate this finding in an association study involving 759 Caucasians selected from the general Australian population. We found no associations with personality traits (including neuroticism, negative affect and behavioral inhibition), anxiety and depressive symptoms, or alcohol misuse.

Original language	English
Pages (from-to)	449-451
Number of pages	3
Journal	Molecular Psychiatry
Volume	3
Issue number	5
DOIs	https://doi.org/10.1038/sj.mp.4000424
Publication status	Published - 1998

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abstract = "A functional polymorphism in the regulatory region of the serotonin transporter gene has been reported to be associated with anxiety-related personality traits. We attempted to replicate this finding in an association study involving 759 Caucasians selected from the general Australian population. We found no associations with personality traits (including neuroticism, negative affect and behavioral inhibition), anxiety and depressive symptoms, or alcohol misuse.",

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AU - Körten, A. E.

AU - Rodgers, B.

AU - Tan, X.

AU - Easteal, S.

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AB - A functional polymorphism in the regulatory region of the serotonin transporter gene has been reported to be associated with anxiety-related personality traits. We attempted to replicate this finding in an association study involving 759 Caucasians selected from the general Australian population. We found no associations with personality traits (including neuroticism, negative affect and behavioral inhibition), anxiety and depressive symptoms, or alcohol misuse.

KW - Alcohol abuse

KW - Anxiety

KW - Depression

KW - Extraversion

KW - Genetics

KW - Neuroticism

KW - Psychoticism

KW - Serotonin transport

UR - https://www.scopus.com/pages/publications/0031687006

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ER -

An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms

Abstract

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