Apolipoprotein E genotype and temperament: A longitudinal study from infancy to the late teens

Anthony F. Jorm; Margot Prior; Ann Sanson; Diana Smart; Yafei Zhang; Simon Easteal

doi:10.1097/01.PSY.0000077506.29218.60

Apolipoprotein E genotype and temperament: A longitudinal study from infancy to the late teens

Anthony F. Jorm^*, Margot Prior, Ann Sanson, Diana Smart, Yafei Zhang, Simon Easteal

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Objective: To replicate an earlier Finnish study by Keltikangas-Järvinen et al. (5) reporting that the APOE genotype is associated with temperamental traits involving increased activity. Methods: DNA was collected from 683 Australian children who had participated in a longitudinal study of childhood temperament from 4 to 8 months up to 17 to 18 years. Associations were examined between APOE genotype and a range of measures of activity and hyperactivity. Results: No associations were found. Conclusions: The earlier Finnish finding could not be replicated despite adequate statistical power.

Original language	English
Pages (from-to)	662-664
Number of pages	3
Journal	Psychosomatic Medicine
Volume	65
Issue number	4
DOIs	https://doi.org/10.1097/01.PSY.0000077506.29218.60
Publication status	Published - Jul 2003

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title = "Apolipoprotein E genotype and temperament: A longitudinal study from infancy to the late teens",

abstract = "Objective: To replicate an earlier Finnish study by Keltikangas-J{\"a}rvinen et al. (5) reporting that the APOE genotype is associated with temperamental traits involving increased activity. Methods: DNA was collected from 683 Australian children who had participated in a longitudinal study of childhood temperament from 4 to 8 months up to 17 to 18 years. Associations were examined between APOE genotype and a range of measures of activity and hyperactivity. Results: No associations were found. Conclusions: The earlier Finnish finding could not be replicated despite adequate statistical power.",

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AU - Sanson, Ann

AU - Smart, Diana

AU - Zhang, Yafei

AU - Easteal, Simon

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AB - Objective: To replicate an earlier Finnish study by Keltikangas-Järvinen et al. (5) reporting that the APOE genotype is associated with temperamental traits involving increased activity. Methods: DNA was collected from 683 Australian children who had participated in a longitudinal study of childhood temperament from 4 to 8 months up to 17 to 18 years. Associations were examined between APOE genotype and a range of measures of activity and hyperactivity. Results: No associations were found. Conclusions: The earlier Finnish finding could not be replicated despite adequate statistical power.

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Apolipoprotein E genotype and temperament: A longitudinal study from infancy to the late teens

Abstract

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