Abstract
The kinetics of the thermal C-C-cleavage reaction of the dimer of sarcosine anhydride 5 has been investigated between 295 and 333 °C in mesitylene. From the temperature dependence and from the release of strain on dissociation the cyclic α-peptide radical 6 was calculated to have a radical stabilization enthalpy (RSE) of -6.3 ± 1.3 kcal / mol thus indicating the absence of a synergistic capto-dative effect.
| Original language | English |
|---|---|
| Pages (from-to) | 7721-7724 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 38 |
| Issue number | 44 |
| DOIs | |
| Publication status | Published - 3 Nov 1997 |
| Externally published | Yes |