Association of a functional polymorphism of the monoamine oxidase A gene promoter with personality and psychiatric symptoms

A. F. Jorm; A. S. Henderson; P. A. Jacomb; H. Christensen; A. E. Korten; B. Rodgers; X. Tan; S. Easteal

doi:10.1097/00041444-200010020-00006

Association of a functional polymorphism of the monoamine oxidase A gene promoter with personality and psychiatric symptoms

A. F. Jorm^*, A. S. Henderson, P. A. Jacomb, H. Christensen, A. E. Korten, B. Rodgers, X. Tan, S. Easteal

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

52 Citations (Scopus)

Abstract

A functional polymorphism in the promoter of the monoamine oxidase gene has recently been described by Sabol et al. This polymorphism is a strong candidate for associations with personality traits and psychiatric symptoms. We report relevant data from a general population sample of 850 Caucasian Australians. We found no associations with anxiety and depression symptoms, with personality traits that predispose to anxiety (neuroticism, behavioral inhibition, negative affect) or to a personality trait related to antisocial behavior (psychoticism). (C) 2000 Lippincott Williams and Wilkins.

Original language	English
Pages (from-to)	87-90
Number of pages	4
Journal	Psychiatric Genetics
Volume	10
Issue number	2
DOIs	https://doi.org/10.1097/00041444-200010020-00006
Publication status	Published - 2000

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title = "Association of a functional polymorphism of the monoamine oxidase A gene promoter with personality and psychiatric symptoms",

abstract = "A functional polymorphism in the promoter of the monoamine oxidase gene has recently been described by Sabol et al. This polymorphism is a strong candidate for associations with personality traits and psychiatric symptoms. We report relevant data from a general population sample of 850 Caucasian Australians. We found no associations with anxiety and depression symptoms, with personality traits that predispose to anxiety (neuroticism, behavioral inhibition, negative affect) or to a personality trait related to antisocial behavior (psychoticism). (C) 2000 Lippincott Williams and Wilkins.",

keywords = "Alcohol abuse, Anxiety, Depression, Extraversion, Genetics, Monoamine oxidase A, Neuroticism, Psychoticism",

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T1 - Association of a functional polymorphism of the monoamine oxidase A gene promoter with personality and psychiatric symptoms

AU - Jorm, A. F.

AU - Henderson, A. S.

AU - Jacomb, P. A.

AU - Christensen, H.

AU - Korten, A. E.

AU - Rodgers, B.

AU - Tan, X.

AU - Easteal, S.

PY - 2000

Y1 - 2000

N2 - A functional polymorphism in the promoter of the monoamine oxidase gene has recently been described by Sabol et al. This polymorphism is a strong candidate for associations with personality traits and psychiatric symptoms. We report relevant data from a general population sample of 850 Caucasian Australians. We found no associations with anxiety and depression symptoms, with personality traits that predispose to anxiety (neuroticism, behavioral inhibition, negative affect) or to a personality trait related to antisocial behavior (psychoticism). (C) 2000 Lippincott Williams and Wilkins.

AB - A functional polymorphism in the promoter of the monoamine oxidase gene has recently been described by Sabol et al. This polymorphism is a strong candidate for associations with personality traits and psychiatric symptoms. We report relevant data from a general population sample of 850 Caucasian Australians. We found no associations with anxiety and depression symptoms, with personality traits that predispose to anxiety (neuroticism, behavioral inhibition, negative affect) or to a personality trait related to antisocial behavior (psychoticism). (C) 2000 Lippincott Williams and Wilkins.

KW - Alcohol abuse

KW - Anxiety

KW - Depression

KW - Extraversion

KW - Genetics

KW - Monoamine oxidase A

KW - Neuroticism

KW - Psychoticism

UR - https://www.scopus.com/pages/publications/0034528484

U2 - 10.1097/00041444-200010020-00006

DO - 10.1097/00041444-200010020-00006

M3 - Article

SN - 0955-8829

VL - 10

SP - 87

EP - 90

JO - Psychiatric Genetics

JF - Psychiatric Genetics

IS - 2

ER -

Association of a functional polymorphism of the monoamine oxidase A gene promoter with personality and psychiatric symptoms

Abstract

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