Association of smoking and personality with a polymorphism of the dopamine transporter gene: Results from a community survey

Anthony F. Jorm*, A. Scott Henderson, Patricia A. Jacomb, Helen Christensen, Ailsa E. Korten, Bryan Rodgers, Xiaoyun Tan, Simon Easteal

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    97 Citations (Scopus)

    Abstract

    In studies that used mixed volunteer samples, Letman et al. [1999: Health Psychol 18:14-20] and Sabol et al. [1999: Health Psychol 18:7-13] reported on an association of smoking with a polymorphism of the dopamine transporter gene. We attempted to replicate this association in a nonvolunteer community sample of 861 Caucasians. No associations were found with either smoking initiation or smoking cessation. Sabol et al. [1999] also reported on an association of the dopamine transporter polymorphism with the personality trait of novelty seeking. However, we failed to find any associations with a range of personality traits, including a scale of fun seeking that correlates with novelty seeking. These negative findings suggest that either the original associations are not replicable or that any association is very small. (C) 2000 Wiley-Liss, Inc.

    Original languageEnglish
    Pages (from-to)331-334
    Number of pages4
    JournalAmerican Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
    Volume96
    Issue number3
    DOIs
    Publication statusPublished - 12 Jun 2000

    Fingerprint

    Dive into the research topics of 'Association of smoking and personality with a polymorphism of the dopamine transporter gene: Results from a community survey'. Together they form a unique fingerprint.

    Cite this