TY - JOUR
T1 - Astd
T2 - The Alternative Splicing and Transcript Diversity database
AU - Koscielny, Gautier
AU - Le Texier, Vincent
AU - Gopalakrishnan, Chellappa
AU - Kumanduri, Vasudev
AU - Riethoven, Jean-Jack
AU - Nardone, Francesco
AU - Stanley, Eleanor
AU - Fallsehr, Christine
AU - Hofmann, Oliver
AU - Kull, Meelis
AU - Harrington, Eoghan
AU - Boue, Stephanie
AU - Eyras, Eduardo
AU - Plass, Mireya
AU - Lopez, Fabrice
AU - Ritchie, William
AU - Moucadel, Virginie
AU - Ara, Takeshi
AU - Pospisil, Heike
AU - Herrmann, Alexander
AU - Reich, Jens G.
AU - Guigo, Roderic
AU - Bork, Peer
AU - Doeberitz, Magnus von Knebel
AU - Vilo, Jaak
AU - Hide, Winston
AU - Apweiler, Rolf
AU - Thanaraj, Thangavel Alphonse
AU - Gautheret, Daniel
PY - 2009/3
Y1 - 2009/3
N2 - The Alternative Splicing and Transcript Diversity database (ASTD) gives access to a vast collection of alternative transcripts that integrate transcription initiation, polyadenylation and splicing variant data. Alternative transcripts are derived from the mapping of transcribed sequences to the complete human, mouse and rat genomes using an extension of the computational pipeline developed for the ASD (Alternative Splicing Database) and ATD (Alternative Transcript Diversity) databases, which are now superseded by ASTD. For the human genome, ASTD identifies splicing variants, transcription initiation variants and polyadenylation variants in 68%, 68% and 62% of the gene set, respectively, consistent with current estimates for transcription variation. Users can access ASTD through a variety of browsing and query tools, including expression state-based queries for the identification of tissue-specific isoforms. Participating laboratories have experimentally validated a subset of ASTD-predicted alternative splice forms and alternative polyadenylation forms that were not previously reported. The ASTD database can be accessed at http://www.ebi.ac.uk/astd. (C) 2008 Elsevier Inc. All rights reserved.
AB - The Alternative Splicing and Transcript Diversity database (ASTD) gives access to a vast collection of alternative transcripts that integrate transcription initiation, polyadenylation and splicing variant data. Alternative transcripts are derived from the mapping of transcribed sequences to the complete human, mouse and rat genomes using an extension of the computational pipeline developed for the ASD (Alternative Splicing Database) and ATD (Alternative Transcript Diversity) databases, which are now superseded by ASTD. For the human genome, ASTD identifies splicing variants, transcription initiation variants and polyadenylation variants in 68%, 68% and 62% of the gene set, respectively, consistent with current estimates for transcription variation. Users can access ASTD through a variety of browsing and query tools, including expression state-based queries for the identification of tissue-specific isoforms. Participating laboratories have experimentally validated a subset of ASTD-predicted alternative splice forms and alternative polyadenylation forms that were not previously reported. The ASTD database can be accessed at http://www.ebi.ac.uk/astd. (C) 2008 Elsevier Inc. All rights reserved.
KW - Alternative initiation
KW - Alternative polyadenylation
KW - Alternative splicing
KW - Alternative transcription
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=anu_research_portal_plus2&SrcAuth=WosAPI&KeyUT=WOS:000263901000004&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.1016/j.ygeno.2008.11.003
DO - 10.1016/j.ygeno.2008.11.003
M3 - Article
C2 - 19059335
SN - 0888-7543
VL - 93
SP - 213
EP - 220
JO - Genomics
JF - Genomics
IS - 3
ER -