Beyond the discovery void: New targets for antibacterial compounds

Claire E. Broughton, Hugo A. Van Den Berg, Alan M. Wemyss, David I. Roper, Alison Rodger

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Antibiotics save many lives, but their efficacy is under threat: overprescription, populationgrowth, and global travel all contribute to the rapid origination and spread of resistantstrains. Exacerbating this threat is the fact that no new major classes of antibioticshave been discovered in the last 30 years: this is the “discovery void.” We discuss thetraditional molecular targets of antibiotics as well as putative novel targets.

Original languageEnglish
Pages (from-to)153-182
Number of pages30
JournalScience Progress
Issue number2
Publication statusPublished - Jun 2016
Externally publishedYes


Dive into the research topics of 'Beyond the discovery void: New targets for antibacterial compounds'. Together they form a unique fingerprint.

Cite this