Biomarkers and cardiac disease in patients with end-stage renal disease on dialysis

Peter E. Hickman*

*Corresponding author for this work

    Research output: Contribution to journalShort surveypeer-review

    12 Citations (Scopus)

    Abstract

    Very soon after troponin was introduced to routine clinical use in the mid-1990s, it was observed that troponin T was often increased in the blood of asymptomatic patients undergoing chronic dialysis for end-stage renal disease. Observation of these patients showed that the presence of troponin T in blood was predictive of a worse outcome for these patients. Cardiac disease is the major cause of death in dialysis patients. This review considers the heterogeneous cardiac disease that is found in these patients and reviews the role of cardiac biomarkers in identifying patients at risk of an adverse outcome.

    Original languageEnglish
    Pages (from-to)115-119
    Number of pages5
    JournalClinical Biochemist Reviews
    Volume32
    Issue number2
    Publication statusPublished - 2011

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