TY - JOUR
T1 - Bioresorbable vascular scaffolds in the routine clinical practice
T2 - Long-term results
AU - Mori-Junco, Ricardo
AU - Furuya-Kanamori, Luis
AU - Salinas, Pablo
AU - Franco, Luis Nombela
AU - Quevedo, Pilar Jimenez
AU - Mejia-Renteria, Hernan
AU - Gonzalo, Nieves
AU - Escaned, Javier
AU - Perez-Vizcayno, Maria Jose
AU - Fernandez-Ortiz, Antonio
AU - Macaya, Carlos
AU - Nunez-Gil, Ivan J.
N1 - Publisher Copyright:
© REC: Interventional Cardiology 2020.
PY - 2020/7
Y1 - 2020/7
N2 - Introduction and objectives: Recent publications suggest that bioresorbable vascular scaffolds (BVS) are associated with an excess of thrombotic complications. We present the real-world, long-term results of a series of patients who received the Absorb BVS (Abbott Vascular, United States). Methods: A total of 213 consecutive patients who received at least 1 BVS between May 2012 and December 2016 were analyzed. The main objective of the study was the rate of target vessel failure, a composite endpoint of infarction or target vessel revascularization and cardiac death. Results: Seventy-five per cent of the patients were men (mean age, 61.4 years). The most common cause for admission was non-ST-elevation myocardial infarction (53.52%). The median follow-up was 44 months [28 months], the rate of the primary endpoint was 6.57% for the first 24 months and 7.98% at the end of the follow-up. Regarding the device, there were 6 cases (2.81%) of thrombosis (definitive, probable or possible) and 10 cases (4.69%) of restenosis. Patients with a past medical history of diabetes mellitus (HR, 1.72; 95%CI, 1.01-2.95; P = .05) and/or chronic oral anticoagulation (HR, 5.71; 95%CI, 1.12-28.94; P = .04) had a higher risk of target vessel failure. Conclusions: In this series of patients, the rate of target vessel failure was similar to the one previously described by randomized clinical trials. Events were more common during the first 2 years of follow-up and in the presence of greater cardiovascular comorbidity.
AB - Introduction and objectives: Recent publications suggest that bioresorbable vascular scaffolds (BVS) are associated with an excess of thrombotic complications. We present the real-world, long-term results of a series of patients who received the Absorb BVS (Abbott Vascular, United States). Methods: A total of 213 consecutive patients who received at least 1 BVS between May 2012 and December 2016 were analyzed. The main objective of the study was the rate of target vessel failure, a composite endpoint of infarction or target vessel revascularization and cardiac death. Results: Seventy-five per cent of the patients were men (mean age, 61.4 years). The most common cause for admission was non-ST-elevation myocardial infarction (53.52%). The median follow-up was 44 months [28 months], the rate of the primary endpoint was 6.57% for the first 24 months and 7.98% at the end of the follow-up. Regarding the device, there were 6 cases (2.81%) of thrombosis (definitive, probable or possible) and 10 cases (4.69%) of restenosis. Patients with a past medical history of diabetes mellitus (HR, 1.72; 95%CI, 1.01-2.95; P = .05) and/or chronic oral anticoagulation (HR, 5.71; 95%CI, 1.12-28.94; P = .04) had a higher risk of target vessel failure. Conclusions: In this series of patients, the rate of target vessel failure was similar to the one previously described by randomized clinical trials. Events were more common during the first 2 years of follow-up and in the presence of greater cardiovascular comorbidity.
KW - Absorb
KW - Bioresorbable scaffolds
KW - Coronary angioplasty
UR - http://www.scopus.com/inward/record.url?scp=85112833113&partnerID=8YFLogxK
U2 - 10.24875/RECICE.M20000099
DO - 10.24875/RECICE.M20000099
M3 - Article
SN - 2604-7306
VL - 2
SP - 168
EP - 174
JO - REC: Interventional Cardiology
JF - REC: Interventional Cardiology
IS - 3
ER -