TY - JOUR
T1 - Breast cancer in the Thai Cohort Study
T2 - An exploratory case-control analysis
AU - Jordan, Susan
AU - Lim, Lynette
AU - Vilainerun, Duangkae
AU - Banks, Emily
AU - Sripaiboonkij, Nintita
AU - Seubsman, Sam ang
AU - Sleigh, Adrian
AU - Bain, Christopher
PY - 2009/10
Y1 - 2009/10
N2 - Breast cancer incidence may be increasing in Thailand but very little research has assessed core breast cancer risk factors in this country. We used baseline questionnaire data from a national cohort study of Thai Open University students in an exploratory case-control study of breast cancer. The study included 43 female cases and 860 age-matched controls selected from the remaining 47,271 female cohort participants. Odds ratios and 95% confidence intervals were calculated using conditional logistic regression. The women were predominantly premenopausal. Taller women had an increased risk of breast cancer (OR = 2.3, 95% CI 1.1-4.8, for height ≥160 cm vs ≤154 cm) as did women with non-insulin dependent diabetes mellitus (OR = 8.4, 95% CI 1.7-41). Women with older siblings had a reduced risk of breast cancer compared to those firstborn (OR = 0.3, 95% CI0.2-0.7). Although limited by small case numbers, our findings suggest substantial increases in breast cancer rates in Thailand could be expected in the future.
AB - Breast cancer incidence may be increasing in Thailand but very little research has assessed core breast cancer risk factors in this country. We used baseline questionnaire data from a national cohort study of Thai Open University students in an exploratory case-control study of breast cancer. The study included 43 female cases and 860 age-matched controls selected from the remaining 47,271 female cohort participants. Odds ratios and 95% confidence intervals were calculated using conditional logistic regression. The women were predominantly premenopausal. Taller women had an increased risk of breast cancer (OR = 2.3, 95% CI 1.1-4.8, for height ≥160 cm vs ≤154 cm) as did women with non-insulin dependent diabetes mellitus (OR = 8.4, 95% CI 1.7-41). Women with older siblings had a reduced risk of breast cancer compared to those firstborn (OR = 0.3, 95% CI0.2-0.7). Although limited by small case numbers, our findings suggest substantial increases in breast cancer rates in Thailand could be expected in the future.
KW - Birth rank
KW - Breast cancer
KW - Etiology
KW - Height
KW - Low-incidence
KW - NIDDM
UR - http://www.scopus.com/inward/record.url?scp=71349087913&partnerID=8YFLogxK
U2 - 10.1016/j.breast.2009.09.004
DO - 10.1016/j.breast.2009.09.004
M3 - Article
SN - 0960-9776
VL - 18
SP - 299
EP - 303
JO - Breast
JF - Breast
IS - 5
ER -