Abstract
Background: Men exhibit higher prevalence of modifiable risk factors, such as
smoking and alcohol consumption, leading to greater cancer incidence and lower
survival rates. Comprehensive evidence on global cancer burden among men,
including disparities by age group and country, is sparse. To address this, the authors
analyzed 30 cancer types among men in 2022, with projections estimated for 2050.
Methods: The 2022 GLOBOCAN estimates were used to describe cancer statistics
for men in 185 countries/territories worldwide. Mortality‐to‐incidence ratios (MIRs)
were calculated by dividing age‐standardized mortality rates by incidence rates.
Results: In 2022, a high MIR (indicating poor survival) was observed among older
men (aged 65 years and older; 61%) for rare cancer types (pancreatic cancer, 91%)
and in countries with low a Human Development Index (HDI; 74%). Between 2022
and 2050, cancer cases are projected to increase from 10.3 million to 19 million
(≥84%). Deaths are projected to increase from 5.4 million to 10.5 million (≥93%),
with a greater than two‐fold increase among men aged 65 years and older (≥117%)
and for low‐HDI and medium‐HDI countries/territories (≥160%). Cancer cases and
deaths are projected to increase among working‐age groups (≥39%) and very‐high‐
HDI countries/territories (≥50%).
Conclusions: Substantial disparities in cancer cases and deaths were observed
among men in 2022, and these are projected to widen by 2050. Strengthening
health infrastructure, enhancing workforce quality and access, fostering national and international collaborations, and promoting universal health coverage are
crucial to reducing cancer disparities and ensuring cancer equity among men
globally.
smoking and alcohol consumption, leading to greater cancer incidence and lower
survival rates. Comprehensive evidence on global cancer burden among men,
including disparities by age group and country, is sparse. To address this, the authors
analyzed 30 cancer types among men in 2022, with projections estimated for 2050.
Methods: The 2022 GLOBOCAN estimates were used to describe cancer statistics
for men in 185 countries/territories worldwide. Mortality‐to‐incidence ratios (MIRs)
were calculated by dividing age‐standardized mortality rates by incidence rates.
Results: In 2022, a high MIR (indicating poor survival) was observed among older
men (aged 65 years and older; 61%) for rare cancer types (pancreatic cancer, 91%)
and in countries with low a Human Development Index (HDI; 74%). Between 2022
and 2050, cancer cases are projected to increase from 10.3 million to 19 million
(≥84%). Deaths are projected to increase from 5.4 million to 10.5 million (≥93%),
with a greater than two‐fold increase among men aged 65 years and older (≥117%)
and for low‐HDI and medium‐HDI countries/territories (≥160%). Cancer cases and
deaths are projected to increase among working‐age groups (≥39%) and very‐high‐
HDI countries/territories (≥50%).
Conclusions: Substantial disparities in cancer cases and deaths were observed
among men in 2022, and these are projected to widen by 2050. Strengthening
health infrastructure, enhancing workforce quality and access, fostering national and international collaborations, and promoting universal health coverage are
crucial to reducing cancer disparities and ensuring cancer equity among men
globally.
| Original language | English |
|---|---|
| Number of pages | 16 |
| Journal | Cancer |
| DOIs | |
| Publication status | Published - 12 Aug 2024 |