C-18 Hydroxylation of gibberellins

Lewis N. Mander; Regan J. Thomson

doi:10.1039/b006044p

C-18 Hydroxylation of gibberellins

Lewis N. Mander^*, Regan J. Thomson

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

A protocol for the hydroxylation of the 18-methyl group in gibberellins has been developed, as demonstrated by the successful synthesis of 18-hydroxy GA₄ methyl ester by means of a tandem process involving the conjugate addition of alkoxide to the α-methylene lactone moiety of a ring A-seco-gibberellin followed by an intramolecular aldol reaction.

Original language	English
Pages (from-to)	2893-2894
Number of pages	2
Journal	Journal of the Chemical Society, Perkin Transactions 1
Issue number	17
DOIs	https://doi.org/10.1039/b006044p
Publication status	Published - 2000

Access to Document

10.1039/b006044p

Cite this

@article{9221809ea47c4580874aa498dd2fbec1,

title = "C-18 Hydroxylation of gibberellins",

abstract = "A protocol for the hydroxylation of the 18-methyl group in gibberellins has been developed, as demonstrated by the successful synthesis of 18-hydroxy GA4 methyl ester by means of a tandem process involving the conjugate addition of alkoxide to the α-methylene lactone moiety of a ring A-seco-gibberellin followed by an intramolecular aldol reaction.",

author = "Mander, \{Lewis N.\} and Thomson, \{Regan J.\}",

year = "2000",

doi = "10.1039/b006044p",

language = "English",

pages = "2893--2894",

journal = "Journal of the Chemical Society, Perkin Transactions 1",

issn = "1472-7781",

publisher = "Chemical Society",

number = "17",

}

TY - JOUR

T1 - C-18 Hydroxylation of gibberellins

AU - Mander, Lewis N.

AU - Thomson, Regan J.

PY - 2000

Y1 - 2000

N2 - A protocol for the hydroxylation of the 18-methyl group in gibberellins has been developed, as demonstrated by the successful synthesis of 18-hydroxy GA4 methyl ester by means of a tandem process involving the conjugate addition of alkoxide to the α-methylene lactone moiety of a ring A-seco-gibberellin followed by an intramolecular aldol reaction.

AB - A protocol for the hydroxylation of the 18-methyl group in gibberellins has been developed, as demonstrated by the successful synthesis of 18-hydroxy GA4 methyl ester by means of a tandem process involving the conjugate addition of alkoxide to the α-methylene lactone moiety of a ring A-seco-gibberellin followed by an intramolecular aldol reaction.

UR - https://www.scopus.com/pages/publications/0034618933

U2 - 10.1039/b006044p

DO - 10.1039/b006044p

M3 - Article

SN - 1472-7781

SP - 2893

EP - 2894

JO - Journal of the Chemical Society, Perkin Transactions 1

JF - Journal of the Chemical Society, Perkin Transactions 1

IS - 17

ER -

C-18 Hydroxylation of gibberellins

Abstract

Access to Document

Other files and links

Fingerprint

Cite this