Calcium channel blockers

Nick Buckley; Andrew Dawson; Ian Whyte

doi:10.1016/j.mpmed.2007.08.025

Calcium channel blockers

Nick Buckley^*, Andrew Dawson, Ian Whyte

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

24 Citations (SciVal)

Abstract

Overdose of calcium channel blockers is potentially lethal. Heart block with marked bradycardia and hypotension are the most important features in overdose. Verapamil and diltiazem are much more dangerous than dihydropyridines. Routine management usually includes IV fluids, activated charcoal, whole bowel irrigation (for controlled-release products) and prolonged ECG monitoring. Antidotes for cardiac effects include calcium, atropine, bicarbonate, insulin, glucagon and vasopressors.

Original language	English
Pages (from-to)	599-602
Number of pages	4
Journal	Medicine (United Kingdom)
Volume	35
Issue number	11
DOIs	https://doi.org/10.1016/j.mpmed.2007.08.025
Publication status	Published - Nov 2007

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10.1016/j.mpmed.2007.08.025

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title = "Calcium channel blockers",

abstract = "Overdose of calcium channel blockers is potentially lethal. Heart block with marked bradycardia and hypotension are the most important features in overdose. Verapamil and diltiazem are much more dangerous than dihydropyridines. Routine management usually includes IV fluids, activated charcoal, whole bowel irrigation (for controlled-release products) and prolonged ECG monitoring. Antidotes for cardiac effects include calcium, atropine, bicarbonate, insulin, glucagon and vasopressors.",

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AU - Dawson, Andrew

AU - Whyte, Ian

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AB - Overdose of calcium channel blockers is potentially lethal. Heart block with marked bradycardia and hypotension are the most important features in overdose. Verapamil and diltiazem are much more dangerous than dihydropyridines. Routine management usually includes IV fluids, activated charcoal, whole bowel irrigation (for controlled-release products) and prolonged ECG monitoring. Antidotes for cardiac effects include calcium, atropine, bicarbonate, insulin, glucagon and vasopressors.

KW - antidotes

KW - calcium channel blockers

KW - cardiotoxicity

KW - poisoning

UR - http://www.scopus.com/inward/record.url?scp=34648863347&partnerID=8YFLogxK

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DO - 10.1016/j.mpmed.2007.08.025

M3 - Review article

SN - 1357-3039

VL - 35

SP - 599

EP - 602

JO - Medicine (United Kingdom)

JF - Medicine (United Kingdom)

IS - 11

ER -

Calcium channel blockers

Abstract

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