Abstract
The cephamycins are often referred to as second-generation cephalosporin antibiotics, although they differ quite markedly from antibiotics such as cefuroxime or cefaclor. A primary attribute of the cephamycins is their resistance to a variety of beta-lactamase types, such as the extended-spectrum betalactamase (ESBLs) and their narrower-spectrum parents, TEM and SHV beta-lactamases. The cephamycins to be discussed in this chapter are cefotetan and cefoxitin primarily, with secondary discussion of cefmetazole and flomoxef.
| Original language | English |
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| Title of host publication | Kucers the Use of Antibiotics |
| Subtitle of host publication | A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs, Seventh Edition |
| Publisher | CRC Press |
| Pages | 403-414 |
| Number of pages | 12 |
| ISBN (Electronic) | 9781498747967 |
| ISBN (Print) | 9781498747950 |
| DOIs | |
| Publication status | Published - 1 Jan 2017 |