Chemical syntheses of the cochliomycins and certain related resorcylic acid lactones

Martin G. Banwell*, Xiang Ma, Benoit Bolte, Yiwen Zhang, Michael Dlugosch

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    6 Citations (Scopus)

    Abstract

    The cochliomycins (7–12) are a group of six resorcylic acid lactones that have recently been isolated from culture broths of marine fungi found in the South China Sea. These natural products have attracted attention as synthetic targets because of (in certain instances) their novel structural features and their capacities to suppress biofouling. This short review summarizes the synthesis of these and some related compounds that have been reported to date, including those developed in the authors’ laboratories.

    Original languageEnglish
    Pages (from-to)4025-4038
    Number of pages14
    JournalTetrahedron Letters
    Volume58
    Issue number43
    DOIs
    Publication statusPublished - 25 Oct 2017

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