Chemical syntheses of the cochliomycins and certain related resorcylic acid lactones

Martin G. Banwell; Xiang Ma; Benoit Bolte; Yiwen Zhang; Michael Dlugosch

doi:10.1016/j.tetlet.2017.08.021

Chemical syntheses of the cochliomycins and certain related resorcylic acid lactones

Martin G. Banwell^*, Xiang Ma, Benoit Bolte, Yiwen Zhang, Michael Dlugosch

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

7 Citations (Scopus)

Abstract

The cochliomycins (7–12) are a group of six resorcylic acid lactones that have recently been isolated from culture broths of marine fungi found in the South China Sea. These natural products have attracted attention as synthetic targets because of (in certain instances) their novel structural features and their capacities to suppress biofouling. This short review summarizes the synthesis of these and some related compounds that have been reported to date, including those developed in the authors’ laboratories.

Original language	English
Pages (from-to)	4025-4038
Number of pages	14
Journal	Tetrahedron Letters
Volume	58
Issue number	43
DOIs	https://doi.org/10.1016/j.tetlet.2017.08.021
Publication status	Published - 25 Oct 2017

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10.1016/j.tetlet.2017.08.021

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title = "Chemical syntheses of the cochliomycins and certain related resorcylic acid lactones",

abstract = "The cochliomycins (7–12) are a group of six resorcylic acid lactones that have recently been isolated from culture broths of marine fungi found in the South China Sea. These natural products have attracted attention as synthetic targets because of (in certain instances) their novel structural features and their capacities to suppress biofouling. This short review summarizes the synthesis of these and some related compounds that have been reported to date, including those developed in the authors{\textquoteright} laboratories.",

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AU - Banwell, Martin G.

AU - Ma, Xiang

AU - Bolte, Benoit

AU - Zhang, Yiwen

AU - Dlugosch, Michael

PY - 2017/10/25

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N2 - The cochliomycins (7–12) are a group of six resorcylic acid lactones that have recently been isolated from culture broths of marine fungi found in the South China Sea. These natural products have attracted attention as synthetic targets because of (in certain instances) their novel structural features and their capacities to suppress biofouling. This short review summarizes the synthesis of these and some related compounds that have been reported to date, including those developed in the authors’ laboratories.

AB - The cochliomycins (7–12) are a group of six resorcylic acid lactones that have recently been isolated from culture broths of marine fungi found in the South China Sea. These natural products have attracted attention as synthetic targets because of (in certain instances) their novel structural features and their capacities to suppress biofouling. This short review summarizes the synthesis of these and some related compounds that have been reported to date, including those developed in the authors’ laboratories.

KW - Natural products

KW - Resorcylic acid lactones

KW - Synthesis

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U2 - 10.1016/j.tetlet.2017.08.021

DO - 10.1016/j.tetlet.2017.08.021

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 43

ER -

Chemical syntheses of the cochliomycins and certain related resorcylic acid lactones

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